SS-31 (Elamipretide)
Fat LossMitochondria-targeted tetrapeptide (elamipretide)Established
Same active peptide as elamipretide. Forzinity received FDA accelerated approval in 2025 for Barth syndrome (โฅ30 kg). Research SS-31 vials are not the approved product.
For research use only.
Key Facts
- CAS
- 736992-21-5
- Molecular Weight (MW)
- 639.8 g/mol
- Half-life
- ~1-2 hours
- Unit
- mg
- Administration Route
- Subcutaneous
- Frequency
- Daily
- Last updated
- 8/23/2026
- Targets
- Cardiolipin
Overview
Same active peptide as elamipretide. Forzinity received FDA accelerated approval in 2025 for Barth syndrome (โฅ30 kg). Research SS-31 vials are not the approved product.
Protocol
- Dosage Range
- 200-500 mcg
- Frequency
- Daily
- Cycle
- 8-12 weeks on, 4-6 off
- Administration Route
- Subcutaneous
- Reconstitution Guide
- 3 mL BAC for 10 mg vial
Science
Mechanism of Action
Cardiolipin-binding tetrapeptide that stabilizes inner-mitochondrial-membrane structure and reduces ROS.
Targets
Cardiolipin
Studies
- SS-31 mechanismโ Journal/year not available
Benefits
Same class as labeled Forzinity
Potential Side Effects
- Injection-site reactions
References
- FDA Forzinity announcementExternal link ยท Year โ
- PMID 18481172External link ยท Year โ