Humanin
CognitiveMitochondrial-derived peptide / researchExperimental
Mitochondrial 24-aa peptide encoded in MT-RNR2, studied for cytoprotection and metabolic signaling. Not FDA-approved.
For research use only.
Key Facts
- CAS
- 330276-69-8
- Molecular Weight (MW)
- 2687.3 g/mol
- Half-life
- ~2-4 hours
- Unit
- mcg
- Administration Route
- Subcutaneous
- Frequency
- Daily
- Last updated
- 8/23/2026
- Targets
- FPRL1IGFBP-3Bax (indirect)
Overview
Mitochondrial 24-aa peptide encoded in MT-RNR2, studied for cytoprotection and metabolic signaling. Not FDA-approved.
Protocol
- Dosage Range
- 100-500 mcg
- Frequency
- Daily
- Cycle
- 4-12 weeks on, 4-6 off
- Administration Route
- Subcutaneous
- Reconstitution Guide
- 3 mL BAC for 5 mg vial
Science
Mechanism of Action
Secreted MDP that can bind FPRL1 and interact with IGFBP-3 / Bax-related pathways, showing anti-apoptotic and insulin-sensitizing effects in models.
Targets
FPRL1IGFBP-3Bax (indirect)
Studies
- Humanin cytoprotective MDP— Journal/year not available
Benefits
Cytoprotection researchMetabolic MDP biology
Potential Side Effects
- Unknown human therapeutic window
References
- PMID 11517249External link · Year —