Adamax
Also known as: Adamantane-modified Semax
Adamax (also called Adamantane-modified Semax) is a synthetic Semax analog in the ACTH fragment analog class. Proposed Semax analog with an adamantane moiety intended to increase lipophilicity and enzymatic stability while retaining melanocortin / neurotrophic pathway activity seen with Semax in preclinical models.
For research use only.
Key Facts
- CAS
- —
- Molecular Weight (MW)
- ≈1033 g/mol
- Half-life
- Not established; designed for improved stability compared with Semax
- FDA status
- Not Approved
- Administration Route
- Intranasal or injectable research context; route varies by supplier/protocol
- Frequency
- Not established
- Last updated
- Sep 26, 2026
- Reviewed
- Aug 30, 2026
- Targets
- Melanocortin pathwaysBDNF-related signaling (proposed)
Vendor price snapshot
Each vendor's price is the median price per mg of its own listings; with fewer than 3 vendors there is no typical range. From public vendor listings collected between Feb 2026 and Jun 2026, so confirm the live price on the vendor site. Peptide Library does not sell peptides.
- Vendors listing this peptide
- 2
- Listed offers
- 4
- Price per mg
- $6.00–$14.00/mg
Research summary
Adamantane-modified Semax analog sold for nootropic research. No study of Adamax is indexed in PubMed; its proposed neurotrophic and stability benefits are design intent carried over from Semax. No FDA approval; human PK is not established.
Peptide Library's Adamax profile summarises the published literature indexed in the Science section, the compound's regulatory status, and research-protocol parameters reported for it. It is a research reference, not medical advice.
Protocol
- Dosage Range
- Not established (research only)
- Frequency
- Not established
- Cycle
- Not established (research only; do not self-administer)
- Administration Route
- Intranasal or injectable research context; route varies by supplier/protocol
- Reconstitution Guide
- Reconstitute per supplier/lab SOP; commonly bacteriostatic water for lyophilized research peptide
- Injection Sites
- Abdomen (subQ)
- Concentration Example
- Example only: 10 mg vial reconstituted with 2 mL = 5 mg/mL
- Expected Onset
- Acute neuropeptide signaling effects are proposed but not clinically established
Not yet checked against primary sources
These figures are compiled from earlier reference material. They have not been verified against FDA labelling, registered trials or published literature, no citation is attached to them, and none of them is a recommended dose. Adamax is queued for dosage evidence review.
Compare reported doses across the whole librarySequence & molecular data
| Amino acid sequence | Ac-MEHFPGP-Adam-NH2 |
|---|---|
| Molecular formula | C50H69N11O11S |
| Molecular weight | ≈1033 g/mol |
| Half-life | Not established; designed for improved stability compared with Semax |
| Appearance | White to off-white lyophilized powder |
| Formulation | Lyophilized Powder |
Identifiers link to the public PubChem, FDA Substance Registration (UNII), ChEMBL and DrugBank records for the same entity.
Science
Mechanism of Action
Proposed Semax analog with an adamantane moiety intended to increase lipophilicity and enzymatic stability while retaining melanocortin / neurotrophic pathway activity seen with Semax in preclinical models.
Origin
Synthetic adamantane-modified ACTH(4–10) analog.
Targets
Studies are being curated for this entry.
Suggest a studyRegulatory & research status
Adamax is not an FDA-approved product. It is sold for laboratory research and has no approved medical use.
| FDA status | Not Approved |
|---|---|
| Availability | Research-Only |
| WADA (sport) | Unknown / Not Listed |
| Library classification | Research-Only |
Benefits
Adamax side effects
Side Effects
- Human safety profile not established
- Possible headache or stimulation based on peptide class reports
- Possible irritation depending on route
Stacking
Common stacking partners
Combinations that include Adamax, with the proposed rationale, an evidence grade and what is not established, are catalogued in the peptide stacks directory.
Storage & stability
Lyophilized (freeze-dried) peptide powder is far more stable than the reconstituted solution. Keep sealed vials cold, dry and away from light; long-term storage is typically frozen, with short-term refrigeration for vials in use.
Once reconstituted in bacteriostatic water, keep the solution refrigerated, avoid repeated freeze–thaw cycles and agitation, and label the vial with the reconstitution date and concentration. Discard any solution that turns cloudy or shows particulates.
Degradation rates differ by sequence: peptides containing methionine, cysteine, asparagine or glutamine are more prone to oxidation and deamidation, so shelf life after reconstitution is compound-specific rather than universal.
Read the full guide: how to store peptides before and after reconstitution →
Source: Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544–575. (PMID 20143256). General guidance for research handling; not product-specific instructions.
Adamax: frequently asked questions
What is Adamax?
Adamantane-modified Semax analog sold for nootropic research. No study of Adamax is indexed in PubMed; its proposed neurotrophic and stability benefits are design intent carried over from Semax. No FDA approval; human PK is not established.
What are the side effects of Adamax?
Adamax has no controlled human safety data, so its side-effect profile is not well established. Effects recorded on this profile include possible headache or stimulation based on peptide class reports and possible irritation depending on route. This is reference information, not medical advice.
How does Adamax work?
Proposed Semax analog with an adamantane moiety intended to increase lipophilicity and enzymatic stability while retaining melanocortin / neurotrophic pathway activity seen with Semax in preclinical models.
Is Adamax FDA approved?
No. Adamax is not approved by the FDA for any indication and is categorised as research-only. It has not been reviewed for safety or efficacy as a medicine, and published research should be read as investigation rather than established use.
What is the half-life of Adamax?
Reported half-life for Adamax is Not established; designed for improved stability compared with Semax. Half-life describes how long the compound persists in circulation, not how long any effect lasts, and published figures vary with route of administration, formulation and the population studied.
What is the amino acid sequence of Adamax?
Adamax has the sequence Ac-MEHFPGP-Adam-NH2, giving a chain of 4 amino acids. Its molecular formula is C50H69N11O11S.
What peptides are similar to Adamax?
Compounds most often compared with Adamax include Semax, N-Acetyl Semax Amidate, Selank and Cerebrolysin. They are grouped by shared mechanism or research area rather than by equivalence, and their regulatory status and evidence base differ.
References
References coming soon.
Suggest a referenceRelated research, comparisons & guides
Related peptides
Compiled by Peptide Library Editorial · Reviewed Aug 30, 2026 · Updated Sep 26, 2026 · Version 5
This Adamax profile is compiled from published literature, public regulatory records and chemical registries. It describes what research reports; it is not medical advice, and nothing here is a dosing recommendation for humans. Peptide Library does not sell peptides. Editorial policy · How profiles are compiled · Report an error
Track Adamax research, inventory and reconstitution in the free Peptide Library app. Get the app for iOS or Android →