NAD+ (Nicotinamide Adenine Dinucleotide)

Fat LossRedox coenzyme / supplementExperimental

Essential redox cofactor sold as IV clinic infusions and oral precursors (NR/NMN). NAD+ itself is not FDA-approved as a drug for anti-aging.

Calculate Dose

For research use only.

Key Facts

CAS: 53-84-9
Molecular Weight (MW): 663.43 g/mol
Half-life: Minutes to hours (rapidly metabolized)
Unit: mg
Administration Route: IV, IM, Oral
Frequency: 1–3x per week (IV/IM) or daily (oral)
Last updated: 8/23/2026
Targets: SirtuinsPARPsRedox enzymes

Overview

Essential redox cofactor sold as IV clinic infusions and oral precursors (NR/NMN). NAD+ itself is not FDA-approved as a drug for anti-aging.

Protocol

Dosage Range: 100–1000 mg
Frequency: 1–3x per week (IV/IM) or daily (oral)
Cycle: 4–12 weeks or ongoing for wellness support
Administration Route: IV, IM, Oral
Reconstitution Guide: Use sterile saline or bacteriostatic water per clinic protocol

Science

Mechanism of Action

Hydride acceptor in dehydrogenase reactions and substrate for sirtuins and PARPs. Direct IV NAD+ pharmacokinetics and anti-aging claims remain under-studied versus oral precursors.