Epitalon
LongevityPineal tetrapeptide / researchExperimental
Synthetic pineal tetrapeptide (AEDG) from Khavinson’s work on epithalamin. Studied for telomerase and circadian research; not FDA-approved.
For research use only.
Key Facts
- CAS
- 307297-39-8
- Molecular Weight (MW)
- 390.35 g/mol
- Half-life
- Short (~10 min)
- Unit
- mg
- Administration Route
- Subcutaneous
- Frequency
- Daily
- Last updated
- 8/23/2026
- Targets
- Telomerase (proposed)Pineal / circadian axis
Overview
Synthetic pineal tetrapeptide (AEDG) from Khavinson’s work on epithalamin. Studied for telomerase and circadian research; not FDA-approved.
Protocol
- Dosage Range
- 5-10 mg daily
- Frequency
- Daily
- Cycle
- 10-20 days on, 4-6 months off
- Administration Route
- Subcutaneous
- Reconstitution Guide
- 2 mL BAC for 50 mg vial
Science
Mechanism of Action
Reported to induce telomerase activity and normalize melatonin secretion in older Russian gerontology studies. Findings have not been confirmed in large Western RCTs.
Targets
Telomerase (proposed)Pineal / circadian axis
Studies
- Epitalon telomerase literature— Journal/year not available
Benefits
Telomere supportSleep improvementAnti-aging
Potential Side Effects
- Mild injection reactions
References
- PMID 12937680External link · Year —