Klotho

CognitiveLongevity protein / researchExperimental

Transmembrane and soluble anti-aging protein that is an FGF23 co-receptor. Shop “Klotho” vials are not an FDA-approved drug and are often fragments or poorly characterized proteins.

Calculate Dose

For research use only.

Key Facts

CAS
Molecular Weight (MW)
~130 kDa (full-length protein)
Half-life
Unit
mg
Administration Route
Research only
Frequency
Last updated
Aug 23, 2026
Targets
FGFR/FGF23Aging-related pathways

Overview

Transmembrane and soluble anti-aging protein that is an FGF23 co-receptor. Shop “Klotho” vials are not an FDA-approved drug and are often fragments or poorly characterized proteins.

Protocol

Dosage Range
Not established as a drug
Frequency
Cycle
Administration Route
Research only
Reconstitution Guide
Injection Sites
AbdomenThigh
Timing Notes
Educational catalog only — not medical advice

Science

Mechanism of Action

α-Klotho complexes with FGF receptors for FGF23 signaling (phosphate/vitamin D) and circulating soluble Klotho is studied for cognitive and vascular aging in animals.

Origin

Endogenous protein; research reagents vary widely.

Targets

FGFR/FGF23Aging-related pathways

Benefits

Aging-biology research

Potential Side Effects

Side Effects

  • Unknown for unregulated vials

References

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