Peptide LibraryMazdutide calculator
Mazdutide is a once-weekly GLP-1 and glucagon receptor dual agonist, approved in China but not by the FDA. Its human dosing comes from phase 3 trials in Chinese adults: 4 and 6 mg in GLORY-1 and 9 mg in GLORY-2. Research vials range from 5 to 15 mg, and at these trial amounts the water volume decides whether a dose fits in one 1 mL syringe; the tables show the arithmetic.
Full research profile: Mazdutide. For any other concentration, use the insulin syringe units converter.
For research use only. Not medical advice. This page does arithmetic; it does not recommend an amount.
Mazdutide reconstitution chart
Concentration and micrograms per mark on a U-100 insulin syringe, by vial size and water added. The peptide amount never changes; only how concentrated it is.
| Vial | + 1 mL water | + 2 mL water | + 3 mL water |
|---|---|---|---|
| 5 mg | 5 mg/mL · 50 mcg per unit | 2.5 mg/mL · 25 mcg per unit | 1.67 mg/mL · 16.7 mcg per unit |
| 6 mg | 6 mg/mL · 60 mcg per unit | 3 mg/mL · 30 mcg per unit | 2 mg/mL · 20 mcg per unit |
| 10 mg | 10 mg/mL · 100 mcg per unit | 5 mg/mL · 50 mcg per unit | 3.33 mg/mL · 33.3 mcg per unit |
| 15 mg | 15 mg/mL · 150 mcg per unit | 7.5 mg/mL · 75 mcg per unit | 5 mg/mL · 50 mcg per unit |
Most-listed Mazdutide vial sizes across vendors we track: 10 mg (3 vendors), 6 mg (2 vendors), 5 mg (1 vendor). Compare prices.
Mazdutide doses from the label and trials, in syringe units
The doses reported in each cited source, converted to U-100 syringe units at common vial and water combinations. This is arithmetic on the cited figures, not a recommendation; a dash means the amount is more than one full 1 mL syringe at that concentration.
GLORY-1 phase 3, once weekly for 48 weeks (Chinese adults with obesity, or overweight with a weight-related condition, n=610)
| Dose | 10 mg + 1 mL (10 mg/mL) | 10 mg + 2 mL (5 mg/mL) | 15 mg + 2 mL (7.5 mg/mL) |
|---|---|---|---|
| 4 mg | 40 units (0.4 mL) | 80 units (0.8 mL) | 53.3 units (0.533 mL) |
| 6 mg | 60 units (0.6 mL) | — | 80 units (0.8 mL) |
Source: Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight. N Engl J Med. 2025
GLORY-2 phase 3, once weekly for 60 weeks (Chinese adults with obesity, 461 analysed)
| Dose | 10 mg + 1 mL (10 mg/mL) | 10 mg + 2 mL (5 mg/mL) | 15 mg + 2 mL (7.5 mg/mL) |
|---|---|---|---|
| 9 mg | 90 units (0.9 mL) | — | — |
Common questions
How many units is 4 mg of Mazdutide?
It depends on the concentration. In a 10 mg vial mixed with 2 mL of bacteriostatic water (5 mg/mL), 4 mg is 0.8 mL, or 80 units on a U-100 insulin syringe. With 3 mL of water instead, the same 4 mg is 120 units.
How much bacteriostatic water do you add to a 10 mg Mazdutide vial?
There is no single correct volume: the amount of peptide is fixed and the water only sets the concentration. For 10 mg, 1 mL gives 10 mg/mL (100 mcg per unit), 2 mL gives 5 mg/mL (50 mcg per unit) and 3 mL gives 3.33 mg/mL (33.3 mcg per unit). More water makes each syringe mark hold less, which makes small amounts easier to measure accurately.
Are the Mazdutide doses on this page recommendations?
No. They are the doses reported in the cited sources (Once-Weekly Mazdutide in Chinese Adults with Obesity or Overweight. N Engl J Med. 2025; Treatment With 9-mg Mazdutide for Weight Reduction in Chinese Adults With Obesity: The GLORY-2 Randomized Clinical Trial. JAMA. 2026), converted to syringe units as arithmetic. Approved products come in their own strengths and devices, and what any person should use is a decision for a licensed clinician.
What does one unit on an insulin syringe mean?
A unit is a volume mark, not an amount of drug. On a U-100 syringe 100 units fill 1 mL, so 10 units is always 0.1 mL; how much peptide those 10 units hold depends only on the concentration you mixed. U-40 syringes use 40 marks per mL, so the same volume reads as a different number of units.