Peptide LibraryThymosin alpha-1 calculator
Thymosin alpha-1 (thymalfasin) is marketed in a number of countries but has no current FDA labelling in the United States. Its randomised trials converge on 1.6 mg per dose at very different intervals: twice weekly as outpatient prevention, every 12 hours in critical illness. Research vials are mostly 10 mg, some 5 mg, several times one 1.6 mg dose, so the tables show where 1.6 mg falls on the syringe at common concentrations.
Full research profile: Thymosin alpha-1. For any other concentration, use the insulin syringe units converter.
For research use only. Not medical advice. This page does arithmetic; it does not recommend an amount.
Thymosin alpha-1 reconstitution chart
Concentration and micrograms per mark on a U-100 insulin syringe, by vial size and water added. The peptide amount never changes; only how concentrated it is.
| Vial | + 1 mL water | + 2 mL water | + 3 mL water |
|---|---|---|---|
| 5 mg | 5 mg/mL · 50 mcg per unit | 2.5 mg/mL · 25 mcg per unit | 1.67 mg/mL · 16.7 mcg per unit |
| 10 mg | 10 mg/mL · 100 mcg per unit | 5 mg/mL · 50 mcg per unit | 3.33 mg/mL · 33.3 mcg per unit |
Most-listed Thymosin alpha-1 vial sizes across vendors we track: 10 mg (26 vendors), 5 mg (12 vendors), 16.4 mg (2 vendors), 0.5 mg (1 vendor). Compare prices.
Thymosin alpha-1 doses from the label and trials, in syringe units
The doses reported in each cited source, converted to U-100 syringe units at common vial and water combinations. This is arithmetic on the cited figures, not a recommendation; a dash means the amount is more than one full 1 mL syringe at that concentration.
Severe acute necrotising pancreatitis trial (2022): 1.6 mg every 12 hours for 7 days, then 1.6 mg once daily for 7 days
| Dose | 5 mg + 2 mL (2.5 mg/mL) | 10 mg + 2 mL (5 mg/mL) |
|---|---|---|
| 1.6 mg | 64 units (0.64 mL) | 32 units (0.32 mL) |
COVID-19 prevention pilot trial (2023): 1.6 mg twice weekly (n=194)
| Dose | 5 mg + 2 mL (2.5 mg/mL) | 10 mg + 2 mL (5 mg/mL) |
|---|---|---|
| 1.6 mg | 64 units (0.64 mL) | 32 units (0.32 mL) |
Common questions
How many units is 1.6 mg of Thymosin alpha-1?
It depends on the concentration. In a 10 mg vial mixed with 2 mL of bacteriostatic water (5 mg/mL), 1.6 mg is 0.32 mL, or 32 units on a U-100 insulin syringe. With 3 mL of water instead, the same 1.6 mg is 48 units.
How much bacteriostatic water do you add to a 10 mg Thymosin alpha-1 vial?
There is no single correct volume: the amount of peptide is fixed and the water only sets the concentration. For 10 mg, 1 mL gives 10 mg/mL (100 mcg per unit), 2 mL gives 5 mg/mL (50 mcg per unit) and 3 mL gives 3.33 mg/mL (33.3 mcg per unit). More water makes each syringe mark hold less, which makes small amounts easier to measure accurately.
Are the Thymosin alpha-1 doses on this page recommendations?
No. They are the doses reported in the cited sources (Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial. Intensive Care Med. 2022; A pilot trial of Thymalfasin (Ta1) to prevent COVID-19 infection and morbidities. Int Immunopharmacol. 2023), converted to syringe units as arithmetic. Approved products come in their own strengths and devices, and what any person should use is a decision for a licensed clinician.
What does one unit on an insulin syringe mean?
A unit is a volume mark, not an amount of drug. On a U-100 syringe 100 units fill 1 mL, so 10 units is always 0.1 mL; how much peptide those 10 units hold depends only on the concentration you mixed. U-40 syringes use 40 marks per mL, so the same volume reads as a different number of units.