MOTS-c calculator

MOTS-c is a mitochondrial-derived peptide with no established human dose. No completed human trial has published one: a registered trial is still recruiting and does not disclose its dose, and the completed phase 1 study often cited for it used an analogue, CB4211. Vendors sell it in large vials, most often 10 mg and also 20 or 40 mg, so the concentration for the same water volume varies fourfold. The tables below show that arithmetic only.

Full research profile: MOTS-c. For any other concentration, use the insulin syringe units converter.

For research use only. Not medical advice. This page does arithmetic; it does not recommend an amount.

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MOTS-c reconstitution chart

Concentration and micrograms per mark on a U-100 insulin syringe, by vial size and water added. The peptide amount never changes; only how concentrated it is.

Vial+ 1 mL water+ 2 mL water+ 3 mL water
10 mg10 mg/mL · 100 mcg per unit5 mg/mL · 50 mcg per unit3.33 mg/mL · 33.3 mcg per unit
20 mg20 mg/mL · 200 mcg per unit10 mg/mL · 100 mcg per unit6.67 mg/mL · 66.7 mcg per unit
40 mg40 mg/mL · 400 mcg per unit20 mg/mL · 200 mcg per unit13.33 mg/mL · 133.3 mcg per unit

Most-listed MOTS-c vial sizes across vendors we track: 10 mg (40 vendors), 40 mg (26 vendors), 20 mg (14 vendors), 50 mg (2 vendors). Compare prices.

Why there is no dose table

No human dose of MOTS-c is established by a published trial, so this page shows concentrations only. The dosage section of the MOTS-c profile lists what the literature does and does not report, with sources.

Common questions

How much bacteriostatic water do you add to a 10 mg MOTS-c vial?

There is no single correct volume: the amount of peptide is fixed and the water only sets the concentration. For 10 mg, 1 mL gives 10 mg/mL (100 mcg per unit), 2 mL gives 5 mg/mL (50 mcg per unit) and 3 mL gives 3.33 mg/mL (33.3 mcg per unit). More water makes each syringe mark hold less, which makes small amounts easier to measure accurately.

What dose does the MOTS-c calculator use?

None. No human dose of MOTS-c is established, so the calculator does not suggest one. It converts a vial size, a water volume and an amount you enter into a volume and syringe units; the tables on this page show concentrations only.

What does one unit on an insulin syringe mean?

A unit is a volume mark, not an amount of drug. On a U-100 syringe 100 units fill 1 mL, so 10 units is always 0.1 mL; how much peptide those 10 units hold depends only on the concentration you mixed. U-40 syringes use 40 marks per mL, so the same volume reads as a different number of units.