Palmitoyl Tripeptide-5
CosmeticCosmetic TGF-ฮฒ mimetic tripeptideExperimental
Palmitoylated KVK tripeptide marketed as a thrombospondin-derived collagen booster (Syn-Coll). Cosmetic active.
For research use only.
Key Facts
- CAS
- 623172-55-4
- Molecular Weight (MW)
- โ
- Half-life
- Topical; systemic PK not established
- Unit
- mcg
- Administration Route
- Topical
- Frequency
- โ
- Last updated
- 8/23/2026
- Targets
- TGF-ฮฒ pathway (claimed)Collagen I
Overview
Palmitoylated KVK tripeptide marketed as a thrombospondin-derived collagen booster (Syn-Coll). Cosmetic active.
Protocol
- Dosage Range
- Per cosmetic formulation
- Frequency
- โ
- Cycle
- โ
- Administration Route
- Topical
- Reconstitution Guide
- โ
Science
Mechanism of Action
Proposed to activate TGF-ฮฒโrelated collagen synthesis in dermal fibroblasts in supplier and small cosmetic studies.
Targets
TGF-ฮฒ pathway (claimed)Collagen I
Studies
- Palmitoyl tripeptide-5 cosmetic literatureโ Journal/year not available
Benefits
Firmness-claim cosmetics
Potential Side Effects
- Irritation
References
- PubChem Pal-KVKExternal link ยท Year โ