Palmitoyl Tetrapeptide-7
CosmeticCosmetic matrikineExperimental
Palmitoylated GQPR tetrapeptide used to reduce IL-6 in stressed skin models and paired with pal-tripeptide-1 in Matrixyl 3000.
For research use only.
Key Facts
- CAS
- 221227-05-0
- Molecular Weight (MW)
- ≈694.9 g/mol
- Half-life
- Topical; systemic PK not established
- Unit
- mcg
- Administration Route
- Topical
- Frequency
- —
- Last updated
- 8/23/2026
- Targets
- IL-6 / dermal inflammation (cosmetic models)
Overview
Palmitoylated GQPR tetrapeptide used to reduce IL-6 in stressed skin models and paired with pal-tripeptide-1 in Matrixyl 3000.
Protocol
- Dosage Range
- Per cosmetic formulation
- Frequency
- —
- Cycle
- —
- Administration Route
- Topical
- Reconstitution Guide
- —
Science
Mechanism of Action
Claimed to downregulate UV-induced IL-6 in keratinocyte/fibroblast models, supporting a quieter inflammatory tone in aging skin.
Targets
IL-6 / dermal inflammation (cosmetic models)
Studies
- Palmitoyl peptides in cosmetics— Journal/year not available
Benefits
Anti-inflammatory cosmetic claims
Potential Side Effects
- Irritation uncommon
References
- PubChem Pal-GQPRExternal link · Year —