Palmitoyl Tripeptide-1
CosmeticCosmetic copper-free GHK analogExperimental
Palmitoylated GHK used as a topical matrikine (often with pal-tetrapeptide-7). Cosmetic ingredient, not a drug.
For research use only.
Key Facts
- CAS
- 147732-56-7
- Molecular Weight (MW)
- ≈578.8 g/mol
- Half-life
- Topical; systemic PK not established
- Unit
- mcg
- Administration Route
- Topical
- Frequency
- —
- Last updated
- 8/23/2026
- Targets
- Dermal fibroblasts
Overview
Palmitoylated GHK used as a topical matrikine (often with pal-tetrapeptide-7). Cosmetic ingredient, not a drug.
Protocol
- Dosage Range
- Per cosmetic formulation
- Frequency
- —
- Cycle
- —
- Administration Route
- Topical
- Reconstitution Guide
- —
Science
Mechanism of Action
Delivers the GHK sequence with a fatty-acid tail for skin penetration; stimulates ECM markers in fibroblast assays.
Targets
Dermal fibroblasts
Studies
- GHK peptide skin review— Journal/year not available
Benefits
Topical remodeling cosmetics
Potential Side Effects
- Irritation
References
- PMID 18644225External link · Year —