N-Acetyl Semax Amidate
CognitiveModified Semax analog / researchExperimental
N-acetylated, C-amidated Semax analog sold for nootropic research, intended to resist peptidases versus standard Semax. Not FDA-approved.
For research use only.
Key Facts
- CAS
- —
- Molecular Weight (MW)
- —
- Half-life
- —
- Unit
- mg
- Administration Route
- Nasal
- Frequency
- Research-dependent
- Last updated
- 8/23/2026
- Targets
- Melanocortin-related CNS pathwaysBDNF (by analogy to Semax)
Overview
N-acetylated, C-amidated Semax analog sold for nootropic research, intended to resist peptidases versus standard Semax. Not FDA-approved.
Protocol
- Dosage Range
- Often discussed as nasal research use; no approved label
- Frequency
- Research-dependent
- Cycle
- —
- Administration Route
- Nasal
- Reconstitution Guide
- —
Science
Mechanism of Action
Same ACTH(4–10)–related backbone as Semax with terminal modifications that may slow degradation. Human PK of the amidated form is not well published.
Targets
Melanocortin-related CNS pathwaysBDNF (by analogy to Semax)
Studies
- Semax neurotrophic review— Journal/year not available
Benefits
Stability-oriented Semax analog research
Potential Side Effects
- Nasal irritation if used IN
- Unknown chronic safety
References
- Semax PMID 16996037External link · Year —