KLOW (GHK-Cu / KPV / BPC-157 / TB-500)
Also known as: KLOW blend, BPC-157 + TB-500 + GHK-Cu + KPV
KLOW (GHK-Cu / KPV / BPC-157 / TB-500), also called KLOW blend or BPC-157 + TB-500 + GHK-Cu + KPV, is a regenerative blend in the Multi-Mechanism Repair class. KLOW is a compounded blend of GHK-Cu, KPV, BPC-157 and TB-500, marketed for tissue repair.
For research use only.
Key Facts
- CAS
- โ
- Molecular Weight (MW)
- Varies
- Half-life
- Varies
- FDA status
- Not Approved
- Administration Route
- Subcutaneous
- Frequency
- Daily
- Last updated
- Sep 26, 2026
- Reviewed
- Aug 30, 2026
- Targets
- Multiple (component-dependent)
Vendor price snapshot
Each vendor counts once, at the median price per mg of its own listings; the typical range is the middle half of vendors. From public vendor listings collected between Dec 2025 and Sep 2026, so confirm the live price on the vendor site. Peptide Library does not sell peptides.
- Vendors listing this peptide
- 26
- Listed offers
- 30
- Median price per mg
- $1.62/mg
- Typical $1.49โ$2.56/mg
Research summary
Vendor regenerative blend (commonly BPC-157, TB-500, GHK-Cu, and KPV). Not a single drug; several components are WADA-prohibited or unapproved.
Peptide Library's KLOW (GHK-Cu / KPV / BPC-157 / TB-500) profile summarises 4 cited studies listed in the Science section, the compound's regulatory status, and research-protocol parameters reported for it. It is a research reference, not medical advice.
Protocol
- Dosage Range
- 1-2 mg total
- Frequency
- Daily
- Cycle
- 4-6 weeks on, 4 off
- Administration Route
- Subcutaneous
- Reconstitution Guide
- 5 mL BAC for 80 mg blend
- Injection Sites
- Midsection
- Concentration Example
- 80 mg / 5 mL = 16 mg/mL
- Timing Notes
- Morning/post-training
- Expected Onset
- 1-2 weeks
Not yet checked against primary sources
These figures are compiled from earlier reference material. They have not been verified against FDA labelling, registered trials or published literature, no citation is attached to them, and none of them is a recommended dose. KLOW (GHK-Cu / KPV / BPC-157 / TB-500) is queued for dosage evidence review.
Compare reported doses across the whole libraryHow to reconstitute KLOW (GHK-Cu / KPV / BPC-157 / TB-500)
- Check the vial size and diluent volume. The profile example for KLOW (GHK-Cu / KPV / BPC-157 / TB-500) is: 5 mL BAC for 80 mg blend.
- Swab both vial stoppers and draw the bacteriostatic water into a sterile syringe.
- Add the water slowly down the inside wall of the peptide vial so it does not jet onto the powder, then swirl gently until the solution is clear. Do not shake.
- Record the resulting concentration: 80 mg / 5 mL = 16 mg/mL.
- Label the vial with the date and concentration, refrigerate it (see Storage & stability below), and use the calculator preset to convert a subcutaneous dose in mcg into syringe units.
Open the peptide calculator with the KLOW (GHK-Cu / KPV / BPC-157 / TB-500) preset โ
Sequence & molecular data
| Amino acid sequence | GHK-Cu: Gly-His-Lys-Cu; KPV: Lys-Pro-Val; BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val; TB-500: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln-OH (thymosin ฮฒ4 17โ23 fragment, as TB-500 is usually sold; some vendors supply full-length thymosin ฮฒ4) |
|---|---|
| Molecular formula | Varies |
| Molecular weight | Varies |
| Half-life | Varies |
| Appearance | White lyophilized powder |
| Formulation | Lyophilized Powder |
Identifiers link to the public PubChem, FDA Substance Registration (UNII), ChEMBL and DrugBank records for the same entity.
Science
Mechanism of Action
KLOW is a compounded blend of GHK-Cu, KPV, BPC-157 and TB-500, marketed for tissue repair. The components act on separate proposed pathways: GHK-Cu on copper-dependent matrix remodelling and collagen synthesis; KPV, the C-terminal tripeptide of alpha-MSH, on NF-kB-mediated inflammatory signalling; BPC-157 on angiogenic and nitric oxide pathways in animal models; and TB-500 on actin sequestration and cell migration. As with any such blend, the combination has no mechanism beyond its parts, no pivotal trial exists for the product, and the pharmacokinetics of co-administration have not been studied. Every component is unapproved.
Origin
Commercial peptide blend.
Targets
Studies
- Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes? (component evidence (ghk-cu (copper peptide)))
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data (component evidence (ghk-cu (copper peptide)))
- A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon (component evidence (kpv))
- Self-Cross-Linked Hydrogel of Cysteamine-Grafted ฮณ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in Rats (component evidence (kpv))
Regulatory & research status
KLOW (GHK-Cu / KPV / BPC-157 / TB-500) is not an FDA-approved product. It is sold for laboratory research and has no approved medical use.
| FDA status | Not Approved |
|---|---|
| Availability | Research-Only |
| WADA (sport) | Unknown / Not Listed |
| Library classification | Research-Only |
Benefits
KLOW (GHK-Cu / KPV / BPC-157 / TB-500) side effects
Side Effects
- Irritation
- Nausea
Contraindications
- Copper allergy
Stacking
Common stacking partners
Combinations that include KLOW (GHK-Cu / KPV / BPC-157 / TB-500), with the proposed rationale, an evidence grade and what is not established, are catalogued in the peptide stacks directory.
Storage & stability
Lyophilized (freeze-dried) peptide powder is far more stable than the reconstituted solution. Keep sealed vials cold, dry and away from light; long-term storage is typically frozen, with short-term refrigeration for vials in use.
Once reconstituted in bacteriostatic water, keep the solution refrigerated, avoid repeated freezeโthaw cycles and agitation, and label the vial with the reconstitution date and concentration. Discard any solution that turns cloudy or shows particulates.
Degradation rates differ by sequence: peptides containing methionine, cysteine, asparagine or glutamine are more prone to oxidation and deamidation, so shelf life after reconstitution is compound-specific rather than universal.
Read the full guide: how to store peptides before and after reconstitution โ
Source: Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544โ575. (PMID 20143256). General guidance for research handling; not product-specific instructions.
KLOW (GHK-Cu / KPV / BPC-157 / TB-500): frequently asked questions
What is KLOW (GHK-Cu / KPV / BPC-157 / TB-500)?
Vendor regenerative blend (commonly BPC-157, TB-500, GHK-Cu, and KPV). Not a single drug; several components are WADA-prohibited or unapproved.
How does KLOW (GHK-Cu / KPV / BPC-157 / TB-500) work?
KLOW is a compounded blend of GHK-Cu, KPV, BPC-157 and TB-500, marketed for tissue repair. The components act on separate proposed pathways: GHK-Cu on copper-dependent matrix remodelling and collagen synthesis; KPV, the C-terminal tripeptide of alpha-MSH, on NF-kB-mediated inflammatory signalling; BPC-157 on angiogenic and nitric oxide pathways in animal models; and TB-500 on actin sequestration and cell migration.
Is KLOW (GHK-Cu / KPV / BPC-157 / TB-500) FDA approved?
No. KLOW (GHK-Cu / KPV / BPC-157 / TB-500) is not approved by the FDA for any indication and is categorised as research-only. It has not been reviewed for safety or efficacy as a medicine, and published research should be read as investigation rather than established use.
What is the half-life of KLOW (GHK-Cu / KPV / BPC-157 / TB-500)?
Reported half-life for KLOW (GHK-Cu / KPV / BPC-157 / TB-500) is Varies. Half-life describes how long the compound persists in circulation, not how long any effect lasts, and published figures vary with route of administration, formulation and the population studied.
What is the amino acid sequence of KLOW (GHK-Cu / KPV / BPC-157 / TB-500)?
KLOW is a blend, not a single peptide. Its components are GHK-Cu (Gly-His-Lys copper complex), KPV (Lys-Pro-Val), BPC-157 (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) and TB-500, which is usually the acetylated thymosin ฮฒ4 fragment Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln rather than the full 43-residue protein. There is no single molecular formula; composition depends on the vial.
What peptides are similar to KLOW (GHK-Cu / KPV / BPC-157 / TB-500)?
Compounds most often compared with KLOW (GHK-Cu / KPV / BPC-157 / TB-500) include GHK-Cu (Copper Peptide), KPV, BPC-157 and TB-500 (Thymosin Beta-4 fragment). They are grouped by shared mechanism or research area rather than by equivalence, and their regulatory status and evidence base differ.
References
- WADA Prohibited List 2026External reference
- Component evidence (GHK-Cu (Copper Peptide)) โ Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?External reference
- Component evidence (GHK-Cu (Copper Peptide)) โ Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene DataExternal reference
- Component evidence (KPV) โ A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colonExternal reference
- Component evidence (KPV) โ Self-Cross-Linked Hydrogel of Cysteamine-Grafted ฮณ-Polyglutamic Acid Stabilized Tripeptide KPV for Alleviating TNBS-Induced Ulcerative Colitis in RatsExternal reference
Related research, comparisons & guides
- GLOW Peptide Blend: What Is Actually in the Vial
- KLOW vs GLOW: What Adding KPV Changes, and What It Does Not
- The Wolverine Stack: What It Is and Where the Name Came From
- KLOW Peptide Blend: GLOW Plus KPV, and What That Addition Changes
- BPC-157 and TB-500: Why Blended Vials Break the Usual Math
- Peptide dosage chart: dose, route and frequencyCategory
- Peptide calculator with the KLOW (GHK-Cu / KPV / BPC-157 / TB-500) preset
- How to store peptides before and after reconstitution
Related peptides
Compiled by Peptide Library Editorial ยท Reviewed Aug 30, 2026 ยท Updated Sep 26, 2026 ยท Version 2
This KLOW (GHK-Cu / KPV / BPC-157 / TB-500) profile is compiled from published literature (4 cited studies linked above), public regulatory records and chemical registries. It describes what research reports; it is not medical advice, and nothing here is a dosing recommendation for humans. Peptide Library does not sell peptides. Editorial policy ยท How profiles are compiled ยท Report an error
Track KLOW (GHK-Cu / KPV / BPC-157 / TB-500) research, inventory and reconstitution in the free Peptide Library app. Get the app for iOS or Android โ