GHRP-2 + Ipamorelin Blend
Also known as: Dual GHS blend
GHRP-2 + Ipamorelin Blend (also called Dual GHS blend) is a research peptide in the Growth Hormone Secretagogue class. This blend combines two agonists at the same receptor, growth hormone secretagogue receptor 1a. Because both act at that single target, combining them does not recruit an additional mechanism the way pairing a secretagogue with a GHRH analog does; it primarily increases total receptor occupancy.
For research use only.
Key Facts
- CAS
- —
- Molecular Weight (MW)
- Mixture
- Half-life
- Short; both ~1–2 h combined activity
- FDA status
- Not Approved
- Administration Route
- Subcutaneous (research)
- Frequency
- —
- Last updated
- Aug 30, 2026
- Reviewed
- Aug 30, 2026
- Targets
- GHSR
Research summary
Blend of two ghrelin-receptor agonists. Both GHRP-2 (pralmorelin) and ipamorelin are WADA S2. Not FDA-approved as a combination.
Peptide Library's GHRP-2 + Ipamorelin Blend profile summarises 4 cited studies listed in the Science section, the compound's regulatory status, and research-protocol parameters reported for it. It is a research reference, not medical advice.
Protocol
- Dosage Range
- Not established
- Frequency
- —
- Cycle
- —
- Administration Route
- Subcutaneous (research)
- Reconstitution Guide
- —
- Timing Notes
- Used together to increase GH/IGF axis stimulation in research.
Not yet checked against primary sources
These figures are compiled from earlier reference material. They have not been verified against FDA labelling, registered trials or published literature, no citation is attached to them, and none of them is a recommended dose. GHRP-2 + Ipamorelin Blend is queued for dosage evidence review.
Compare reported doses across the whole librarySequence & molecular data
| Molecular formula | Mixture of C45H55N9O6 (GHRP-2) and C38H49N9O5 (Ipamorelin) |
|---|---|
| Molecular weight | Mixture |
| Half-life | Short; both ~1–2 h combined activity |
| Appearance | White lyophilized powder blend |
| Formulation | Lyophilized Powder |
Identifiers link to the public PubChem, FDA Substance Registration (UNII), ChEMBL and DrugBank records for the same entity.
Science
Mechanism of Action
This blend combines two agonists at the same receptor, growth hormone secretagogue receptor 1a. Because both act at that single target, combining them does not recruit an additional mechanism the way pairing a secretagogue with a GHRH analog does; it primarily increases total receptor occupancy. The practical consequence is that the profile shifts toward that of the less selective component: GHRP-2 raises ACTH, cortisol and prolactin more than ipamorelin does, so the combination tends to carry more of those effects than ipamorelin alone while offering no new pharmacological pathway. No controlled human data exists for this specific combination.
Origin
Combination of two synthetic GHRPs.
Targets
Studies
- Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LN (component evidence (pralmorelin (ghrp-2)))
- Identification of a novel growth hormone releasing peptide (a glycine analogue of GHRP-2) in a seized injection vial (component evidence (pralmorelin (ghrp-2)))
- The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus (component evidence (ipamorelin))
- The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism (component evidence (ipamorelin))
Regulatory & research status
GHRP-2 + Ipamorelin Blend is not an FDA-approved product. It is sold for laboratory research and has no approved medical use.
| FDA status | Not Approved |
|---|---|
| Availability | Research-Only |
| WADA (sport) | Banned in Sport |
| Library classification | Research-Only |
Benefits
GHRP-2 + Ipamorelin Blend side effects
Side Effects
- Hunger
- Cortisol/prolactin rise from GHRP-2
- Water retention
Storage & stability
Lyophilized (freeze-dried) peptide powder is far more stable than the reconstituted solution. Keep sealed vials cold, dry and away from light; long-term storage is typically frozen, with short-term refrigeration for vials in use.
Once reconstituted in bacteriostatic water, keep the solution refrigerated, avoid repeated freeze–thaw cycles and agitation, and label the vial with the reconstitution date and concentration. Discard any solution that turns cloudy or shows particulates.
Degradation rates differ by sequence: peptides containing methionine, cysteine, asparagine or glutamine are more prone to oxidation and deamidation, so shelf life after reconstitution is compound-specific rather than universal.
Read the full guide: how to store peptides before and after reconstitution →
Source: Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544–575. (PMID 20143256). General guidance for research handling; not product-specific instructions.
GHRP-2 + Ipamorelin Blend: frequently asked questions
What is GHRP-2 + Ipamorelin Blend?
Blend of two ghrelin-receptor agonists. Both GHRP-2 (pralmorelin) and ipamorelin are WADA S2. Not FDA-approved as a combination.
How does GHRP-2 + Ipamorelin Blend work?
This blend combines two agonists at the same receptor, growth hormone secretagogue receptor 1a. Because both act at that single target, combining them does not recruit an additional mechanism the way pairing a secretagogue with a GHRH analog does; it primarily increases total receptor occupancy.
Is GHRP-2 + Ipamorelin Blend FDA approved?
No. GHRP-2 + Ipamorelin Blend is not approved by the FDA for any indication and is categorised as research-only. It has not been reviewed for safety or efficacy as a medicine, and published research should be read as investigation rather than established use.
What is the half-life of GHRP-2 + Ipamorelin Blend?
Reported half-life for GHRP-2 + Ipamorelin Blend is Short; both ~1–2 h combined activity. Half-life describes how long the compound persists in circulation, not how long any effect lasts, and published figures vary with route of administration, formulation and the population studied.
Is GHRP-2 + Ipamorelin Blend banned in sport?
GHRP-2 + Ipamorelin Blend is recorded here as prohibited in sport. Athletes subject to anti-doping rules should check the current WADA Prohibited List directly, since it is revised annually and classifications change.
What peptides are similar to GHRP-2 + Ipamorelin Blend?
Compounds most often compared with GHRP-2 + Ipamorelin Blend include Ipamorelin, GHRP-6, GHRP-1 and Pralmorelin (GHRP-2). They are grouped by shared mechanism or research area rather than by equivalence, and their regulatory status and evidence base differ.
References
- WADA Prohibited List 2026External reference
- Component evidence (Pralmorelin (GHRP-2)) — Pralmorelin: GHRP 2, GPA 748, growth hormone-releasing peptide 2, KP-102 D, KP-102 LN, KP-102D, KP-102LNExternal reference
- Component evidence (Pralmorelin (GHRP-2)) — Identification of a novel growth hormone releasing peptide (a glycine analogue of GHRP-2) in a seized injection vialExternal reference
- Component evidence (Ipamorelin) — The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicusExternal reference
- Component evidence (Ipamorelin) — The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanismExternal reference
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Compiled by Peptide Library Editorial · Reviewed Aug 30, 2026 · Updated Aug 30, 2026 · Version 1
This GHRP-2 + Ipamorelin Blend profile is compiled from published literature (4 cited studies linked above), public regulatory records and chemical registries. It describes what research reports; it is not medical advice, and nothing here is a dosing recommendation for humans. Peptide Library does not sell peptides. Editorial policy · How profiles are compiled · Report an error
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