sh-Oligopeptide-1 (Human EGF)
CosmeticCosmetic EGF / researchExperimental
Recombinant or fragment EGF used in cosmetics as sh-oligopeptide-1. Topical cosmetic; injectable EGF is a different, unapproved proposition.
For research use only.
Key Facts
- CAS
- 62253-63-8
- Molecular Weight (MW)
- ≈6.2 kDa (protein growth factor)
- Half-life
- Topical; systemic PK not applicable
- Unit
- mcg
- Administration Route
- Topical
- Frequency
- —
- Last updated
- 8/23/2026
- Targets
- EGFR
Overview
Recombinant or fragment EGF used in cosmetics as sh-oligopeptide-1. Topical cosmetic; injectable EGF is a different, unapproved proposition.
Protocol
- Dosage Range
- Per cosmetic formulation
- Frequency
- —
- Cycle
- —
- Administration Route
- Topical
- Reconstitution Guide
- —
Science
Mechanism of Action
Binds EGFR to stimulate keratinocyte and fibroblast proliferation in wound and cosmetic models. Intact protein has poor passive skin penetration.
Targets
EGFR
Studies
- EGF in wound healing— Journal/year not available
Benefits
Wound and cosmetic EGF literature
Potential Side Effects
- Irritation
- Theoretical EGFR stimulation concerns
References
- PMID 3315373External link · Year —