Dihexa
CognitiveAngiotensin IV analog / nootropic researchExperimental
Orally active angiotensin IV analog that potentiates HGF/c-Met signaling in animal memory models. Not FDA-approved; human safety is not established.
For research use only.
Key Facts
- CAS
- 1401708-83-5
- Molecular Weight (MW)
- 504.70 g/mol
- Half-life
- Oral; long CNS residence reported in animals
- Unit
- mg
- Administration Route
- Subcutaneous
- Frequency
- —
- Last updated
- 8/23/2026
- Targets
- HGF / c-Met
Overview
Orally active angiotensin IV analog that potentiates HGF/c-Met signaling in animal memory models. Not FDA-approved; human safety is not established.
Protocol
- Dosage Range
- —
- Frequency
- —
- Cycle
- —
- Administration Route
- Subcutaneous
- Reconstitution Guide
- —
Science
Mechanism of Action
Binds HGF and enhances c-Met receptor activation, promoting synaptogenesis in hippocampal models. Potency in rodents does not establish clinical cognitive benefit.
Targets
HGF / c-Met
Studies
- Dihexa synaptogenic angiotensin IV analog— Journal/year not available
Benefits
Synaptogenesis researchOral nootropic probe
Potential Side Effects
- Unknown human AE profile
- Theoretical growth-factor risks
References
- PMID 23108585External link · Year —