Pentadeca Arginate
Pentadeca Arginate is a research peptide in the Wound Healing / Cytoprotective class. The peptide sequence is the same as BPC-157, so the proposed mechanism is the same: angiogenic signalling through VEGFR2 and FAK pathways, modulation of the nitric oxide system, and cytoprotective effects on gastrointestinal mucosa reported in animal models.
For research use only.
Key Facts
- CAS
- —
- Molecular Weight (MW)
- —
- Half-life
- —
- FDA status
- Not Approved
- Administration Route
- subcutaneous
- Frequency
- —
- Last updated
- Aug 30, 2026
- Reviewed
- Aug 30, 2026
Research summary
Arginate salt form of the BPC-157 pentadecapeptide, marketed as a more stable alternative to the acetate salt. Not FDA-approved. Published research on the arginate form specifically is minimal; nearly all available evidence concerns BPC-157 itself.
Peptide Library's Pentadeca Arginate profile summarises 5 cited studies listed in the Science section, the compound's regulatory status, and research-protocol parameters reported for it. It is a research reference, not medical advice.
Protocol
- Dosage Range
- —
- Frequency
- —
- Cycle
- —
- Administration Route
- subcutaneous
- Reconstitution Guide
- —
Science
Mechanism of Action
The peptide sequence is the same as BPC-157, so the proposed mechanism is the same: angiogenic signalling through VEGFR2 and FAK pathways, modulation of the nitric oxide system, and cytoprotective effects on gastrointestinal mucosa reported in animal models. The arginate counter-ion is claimed to improve stability in solution, but comparative pharmacokinetic data between the salt forms has not been published.
Studies
- Multifunctionality and Possible Medical Application of the BPC 157 Peptide (class-level)
- Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing (class-level)
- Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review (class-level evidence)
- Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain (class-level evidence)
- Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing (class-level evidence)
Regulatory & research status
Pentadeca Arginate is not an FDA-approved product. It is sold for laboratory research and has no approved medical use.
| FDA status | Not Approved |
|---|---|
| Research status | Research-only compound; no approval pathway listed |
| Availability | Research-Only |
| WADA (sport) | Unknown / Not Listed |
| Library classification | Research-Only |
Benefits
—
Potential Side Effects
No side effects listed yet for this entry.
Storage & stability
Lyophilized (freeze-dried) peptide powder is far more stable than the reconstituted solution. Keep sealed vials cold, dry and away from light; long-term storage is typically frozen, with short-term refrigeration for vials in use.
Once reconstituted in bacteriostatic water, keep the solution refrigerated, avoid repeated freeze–thaw cycles and agitation, and label the vial with the reconstitution date and concentration. Discard any solution that turns cloudy or shows particulates.
Degradation rates differ by sequence: peptides containing methionine, cysteine, asparagine or glutamine are more prone to oxidation and deamidation, so shelf life after reconstitution is compound-specific rather than universal.
Read the full guide: how to store peptides before and after reconstitution →
Source: Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544–575. (PMID 20143256). General guidance for research handling; not product-specific instructions.
Pentadeca Arginate: frequently asked questions
What is Pentadeca Arginate?
Arginate salt form of the BPC-157 pentadecapeptide, marketed as a more stable alternative to the acetate salt. Not FDA-approved. Published research on the arginate form specifically is minimal; nearly all available evidence concerns BPC-157 itself.
How does Pentadeca Arginate work?
The peptide sequence is the same as BPC-157, so the proposed mechanism is the same: angiogenic signalling through VEGFR2 and FAK pathways, modulation of the nitric oxide system, and cytoprotective effects on gastrointestinal mucosa reported in animal models. The arginate counter-ion is claimed to improve stability in solution, but comparative pharmacokinetic data between the salt forms has not been published.
Is Pentadeca Arginate FDA approved?
No. Pentadeca Arginate is not approved by the FDA for any indication and is categorised as research-only. It has not been reviewed for safety or efficacy as a medicine, and published research should be read as investigation rather than established use.
What peptides are similar to Pentadeca Arginate?
Compounds most often compared with Pentadeca Arginate include BPC-157, TB-500 (Thymosin Beta-4 fragment), Thymosin β4 (Tβ4) and GHK-Cu (Copper Peptide). They are grouped by shared mechanism or research area rather than by equivalence, and their regulatory status and evidence base differ.
References
- Parent-compound evidence — Multifunctionality and Possible Medical Application of the BPC 157 Peptide. Pharmaceuticals, 2025External reference
- Parent-compound evidence — Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing, 2025External reference
- Class-level evidence — Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review — HSS J, 2025External reference
- Class-level evidence — Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain — Altern Ther Health Med, 2021External reference
- Class-level evidence — Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing — Cell Tissue Res, 2019External reference
Related research, comparisons & guides
Related peptides
Compiled by Peptide Library Editorial · Reviewed Aug 30, 2026 · Updated Aug 30, 2026 · Version 1
This Pentadeca Arginate profile is compiled from published literature (5 cited studies linked above), public regulatory records and chemical registries. It describes what research reports; it is not medical advice, and nothing here is a dosing recommendation for humans. Peptide Library does not sell peptides. Editorial policy · How profiles are compiled · Report an error
Track Pentadeca Arginate research, inventory and reconstitution in the free Peptide Library app. Get the app for iOS or Android →