Peptide Library

Human study PLS-00207

Associations of Serum MOTS-c with Exercise Capacity and Antioxidant Markers in Young Males: A Cross-Sectional Study.

Cross-sectional study · 30 participants enrolled · not included in the assessments (wrong compound)

Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.

Only the abstract was available. Essential methods may be missing, which limits what can be judged.

Reports of this study

Every publication, registration and abstract describing this one study. Participants are counted once.

  • Associations of Serum MOTS-c with Exercise Capacity and Antioxidant Markers in Young Males: A Cross-Sectional Study.primary · Antioxidants (Basel, Switzerland) · 2026-10-01 · PMID 42939841 · DOI

Design and participants

Design
Cross-sectional study
Population
Healthy young males aged 18 to 25 years, stratified into elite track and field athletes, recreationally active individuals and sedentary controls (10 each)
Conditions
healthy volunteers
Planned enrollment (registry)
Not reported
Enrolled
30
Randomized
Not reported
Completed follow-up
Not reported

Intervention and comparator

What each group received. Related peptides, analogs and combinations are never treated as the compound itself.

    What the authors reported

    As stated in the sources. This is the authors’ account, not Peptide Library’s assessment.

    Adverse events

    None reported. That is not evidence of safety, and how safety was monitored isn’t described.

    The authors concluded (paraphrased): Serum MOTS-c is associated with exercise capacity and circulating antioxidant markers in young males, but the cross-sectional design precludes causal inference.

    Peptide Library’s assessment

    An automated assessment, made by AI separately from the authors’ conclusions and not reviewed by a person. How risk of bias is assessed.

    Limitations

    • other: Endogenous serum MOTS-c was measured; no MOTS-c was administered, so no intervention effect can be assessed.
    • small or imprecise: Only 30 participants in total, 10 per group, per the abstract.
    • confounding: The cross-sectional associations cannot establish causality, as the authors acknowledge in the abstract.
    • abstract only: Only the abstract was available in the record, so methods details were not assessed.

    No risk-of-bias assessment has been published for this study’s results.

    Claims this study informs

    Where each value comes from

    • author_conclusion: PMID 42939841, abstract (last sentence) · extracted by AI (automated, not verified by a person) · abstract only
    • design: PMID 42939841, abstract (sentence 2) · extracted by AI (automated, not verified by a person) · abstract only
    • limitations: PMID 42939841, abstract (last sentence) · extracted by AI (automated, not verified by a person) · abstract only
    • participants: PMID 42939841, abstract (sentence 2) · extracted by AI (automated, not verified by a person) · abstract only
    • population: PMID 42939841, abstract (sentence 2) · extracted by AI (automated, not verified by a person) · abstract only

    • Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.

    These assessments describe published research. Records marked automated were produced by AI under the published methodology and have not been reviewed by a person; they can contain errors. None of this is medical advice, not a statement about any product’s safety for human use, and not a regulatory approval. Peptide Library’s vendor and partner relationships play no part in them (editorial independence).