Human study PLS-00170
Association of thymosin β4 expression with clinicopathological parameters and clinical outcomes of bladder cancer patients.
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
Only the abstract was available. Essential methods may be missing, which limits what can be judged.
Reports of this study
Every publication, registration and abstract describing this one study. Participants are counted once.
- Association of thymosin β4 expression with clinicopathological parameters and clinical outcomes of bladder cancer patients.primary · Neoplasma · 2016-01-01 · PMID 27596300 · DOI
Design and participants
- Design
- Other design
- Population
- Patients with primary bladder transitional cell carcinoma (138 tissue specimens), with normal bladder tissue (24 specimens) for comparison.
- Conditions
- Bladder transitional cell carcinoma
- Planned enrollment (registry)
- Not reported
- Enrolled
- Not reported
- Randomized
- Not reported
- Completed follow-up
- Not reported
Intervention and comparator
What each group received. Related peptides, analogs and combinations are never treated as the compound itself.
What the authors reported
As stated in the sources. This is the authors’ account, not Peptide Library’s assessment.
Adverse events
None reported. That is not evidence of safety, and how safety was monitored isn’t described.
The authors concluded (paraphrased): The authors concluded that Tβ4 expression is correlated with the pathogenesis of bladder transitional cell carcinoma, and that patients with higher Tβ4 expression had shorter survival.
Peptide Library’s assessment
An automated assessment, made by AI separately from the authors’ conclusions and not reviewed by a person. How risk of bias is assessed.
Limitations
- other: The study measured endogenous tissue expression of Tβ4. It did not administer the compound, so it cannot inform its efficacy or safety.
- abstract only: Only the PubMed abstract is available. Methods, funding and conflicts are not described.
- inappropriate population: Study measured endogenous Tβ4 in tumour tissue and gave no Tβ4 treatment, so it does not address administration of the compound.
No risk-of-bias assessment has been published for this study’s results.
Claims this study informs
- Improves dry eye signs and symptoms: not eligible (not primary study) for “Ocular discomfort and corneal staining”
- Is safe for human administration: not eligible (not primary study) for “Adverse events, serious adverse events and discontinuations”
Where each value comes from
- author_conclusion: PMID 27596300, abstract (sentences 8-9) · extracted by AI (automated, not verified by a person) · abstract only
- design: PMID 27596300, abstract (sentence 3) · extracted by AI (automated, not verified by a person) · abstract only
- population: PMID 27596300, abstract (sentence 3) · extracted by AI (automated, not verified by a person) · abstract only
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
These assessments describe published research. Records marked automated were produced by AI under the published methodology and have not been reviewed by a person; they can contain errors. None of this is medical advice, not a statement about any product’s safety for human use, and not a regulatory approval. Peptide Library’s vendor and partner relationships play no part in them (editorial independence).