Human study PLS-00165
Determination of thymosin beta4 and protein in human wound fluid after abdominal surgery.
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
Only the abstract was available. Essential methods may be missing, which limits what can be judged.
Reports of this study
Every publication, registration and abstract describing this one study. Participants are counted once.
- Determination of thymosin beta4 and protein in human wound fluid after abdominal surgery.primary · Annals of the New York Academy of Sciences · 2007-05-10 · PMID 17495244 · DOI
Design and participants
- Design
- Other design
- Population
- Patients after abdominal surgery whose wound fluid was collected by Robinson drainage; number and characteristics not stated
- Conditions
- Abdominal surgery, Surgical wound healing
- Setting
- Postoperative surgical setting; institution not stated
- Planned enrollment (registry)
- Not reported
- Enrolled
- Not reported
- Randomized
- Not reported
- Completed follow-up
- Not reported
- Funding
- Not stated
- Authors’ conflicts
- Not stated
Intervention and comparator
What each group received. Related peptides, analogs and combinations are never treated as the compound itself.
What the authors reported
As stated in the sources. This is the authors’ account, not Peptide Library’s assessment.
Adverse events
None reported. That is not evidence of safety.
Monitoring: Not reported; no compound was administered
The authors concluded (paraphrased): After abdominal surgery, total protein and endogenous thymosin beta4 levels in wound fluid fell over time. Neither thymosin beta10 nor oxidized thymosin beta4 was detected in the wound fluid.
Peptide Library’s assessment
An automated assessment, made by AI separately from the authors’ conclusions and not reviewed by a person. How risk of bias is assessed.
Limitations
- other: Endogenous Tβ4 was only measured and was never administered, so the study gives no information on treatment effects or safety.
- abstract only: Only the abstract is available, and it does not report the number of patients or their characteristics.
- no control group: Wound fluid was measured over time in surgical patients without any comparison group.
- inappropriate population: No thymosin beta4 was given to participants. The study measured the endogenous peptide in surgical wound fluid, so it gives no intervention data.
No risk-of-bias assessment has been published for this study’s results.
Claims this study informs
- Improves dry eye signs and symptoms: not eligible (not primary study) for “Ocular discomfort and corneal staining”
- Is safe for human administration: not eligible (not primary study) for “Adverse events, serious adverse events and discontinuations”
Where each value comes from
- author_conclusion: PMID 17495244, abstract (sentences 4-6) · extracted by AI (automated, not verified by a person) · abstract only
- design: PMID 17495244, abstract (sentences 1-3) · extracted by AI (automated, not verified by a person) · abstract only
- limitations: PMID 17495244, abstract (sentences 1-6) · extracted by AI (automated, not verified by a person) · abstract only
- population: PMID 17495244, abstract (sentences 1-2) · extracted by AI (automated, not verified by a person) · abstract only
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
These assessments describe published research. Records marked automated were produced by AI under the published methodology and have not been reviewed by a person; they can contain errors. None of this is medical advice, not a statement about any product’s safety for human use, and not a regulatory approval. Peptide Library’s vendor and partner relationships play no part in them (editorial independence).