Cognitive & Neuro

• any cognitive claim needs a blood brain barrier story first

  Prerequisite question for this entire category and it's frequently skipped. For a peptide to act centrally it has to reach the brain. The blood brain barrier is selective and most…

  mechanism_firstSenior AnalystOct 9, 2026

  4 replies7 upvotes

• intranasal: what fraction actually reaches the CNS? looking for numbers

  the route gets described as bypassing the blood brain barrier which i think overstates it. anyone have actual numbers

  anxiolytic_qAnalystSep 18, 2026

  0 replies1 upvotes

Discussions are educational and cover published research. Nothing here is individualised medical advice.