Human study PLS-00247
Topical GHK-Cu Gel for Acute Skin Wound Healing
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
Reports of this study
Every publication, registration and abstract describing this one study. Participants are counted once.
- Topical GHK-Cu Gel for Acute Skin Wound Healingregistry entry · NCT07437586 (RECRUITING, no results posted, planned enrollment 60)
Design and participants
- Design
- Other design
- Population
- People with acute standardized cutaneous wounds (punch-biopsy wounds); age, sex and other eligibility details not stated in the record
- Conditions
- Acute standardized cutaneous wounds (punch-biopsy wounds)
- Planned enrollment (registry)
- 60
- Enrolled
- Not reported
- Randomized
- Not reported
- Completed follow-up
- Not reported
Intervention and comparator
What each group received. Related peptides, analogs and combinations are never treated as the compound itself.
- GHK-Cu gel (intervention) · ghk-cu · Topical gel containing the copper(II)-peptide complex GHK-Cu · topical · Not reported assigned
- Vehicle gel (comparator) · Vehicle gel registered as the placebo comparator · placebo · topical · Not reported assigned
What the authors reported
As stated in the sources. This is the authors’ account, not Peptide Library’s assessment.
Adverse events
None reported. That is not evidence of safety, and how safety was monitored isn’t described.
Peptide Library’s assessment
An automated assessment, made by AI separately from the authors’ conclusions and not reviewed by a person. How risk of bias is assessed.
Limitations
- other: Registry entry only, with recruitment ongoing and has_results false. No outcome data are available to appraise.
- selective reporting: The record lists no registered primary or secondary outcomes, so planned outcomes cannot be checked against later reporting.
- inadequate randomization: The registry fields in the record do not state whether allocation to GHK-Cu gel or vehicle gel is randomized, concealed or blinded.
- small or imprecise: Estimated enrollment is only 60 participants across two arms, which limits precision for any eventual effect estimates.
- inappropriate population: Participants have experimental punch-biopsy wounds, not photoaged skin or chronic wounds. This limits applicability to other claims.
No risk-of-bias assessment has been published for this study’s results.
Claims this study informs
- Improves signs of skin aging: not eligible (wrong population) for “Wrinkles and skin quality, measured or rated”
- Is safe for human use: not eligible (insufficient data) for “Adverse events, including skin reactions”
Where each value comes from
- arms: NCT NCT07437586, registry (interventions field) · extracted by AI (automated, not verified by a person)
- design: NCT NCT07437586, registry (study_type and phases fields) · extracted by AI (automated, not verified by a person)
- limitations: NCT NCT07437586, registry (status and has_results fields) · extracted by AI (automated, not verified by a person)
- participants: NCT NCT07437586, registry (enrollment and enrollment_type fields) · extracted by AI (automated, not verified by a person)
- population: NCT NCT07437586, registry (conditions field) · extracted by AI (automated, not verified by a person)
Version 1 · published November 8, 2026 · evidence through November 8, 2026 · research snapshot 2026.1.1 · methodology ev-1 · Automated assessment by AI (claude-opus-5-5 and claude-sonnet-5-5), not reviewed by a person.
These assessments describe published research. Records marked automated were produced by AI under the published methodology and have not been reviewed by a person; they can contain errors. None of this is medical advice, not a statement about any product’s safety for human use, and not a regulatory approval. Peptide Library’s vendor and partner relationships play no part in them (editorial independence).