Peptide Library

Research statistics

Cosyntropin research: publications and trials

What has been published on Cosyntropin: PubMed publications, the kind of evidence they report and registered clinical trials. These are counts of research, not a judgment of whether Cosyntropin works or is safe. For what it is and what the studies found, see the Cosyntropin profile.
Automated weekly refresh · data through November 1, 2026

At a glance

Publications, all years

2,701

Since 1954

Publications in 2026 so far

33

Through November 1, 2026

Human clinical research

54.5%

1,337 of 2,453 classified

Registered clinical trials

39

ClinicalTrials.gov

Randomized controlled trials

125

Publications reporting an RCT in people

Systematic reviews and meta-analyses

9

Preclinical studies

38.5%

843 animal · 98 in vitro · 4 computational

Records that only mention it

848

Not counted above

Status in the library: FDA-approved. Groups: Melanocortin agonists. 248 publications are not yet classified by study type.

What to keep in mind

  • Some completed trials have neither posted results nor a linked results publication.

Publications by year

Cosyntropin publications by year and evidence

1954, Other and not yet classified: 6 of 61955, Other and not yet classified: 1 of 11957, Other and not yet classified: 1 of 11958, Other and not yet classified: 3 of 31959, Other and not yet classified: 1 of 11961, Preclinical (animal, in vitro, computational): 2 of 41961, Other and not yet classified: 2 of 41962, Other and not yet classified: 1 of 11963, Human clinical research: 1 of 101963, Other and not yet classified: 9 of 101964, Other and not yet classified: 11 of 111965, Other and not yet classified: 3 of 31966, Other and not yet classified: 3 of 31967, Human clinical research: 2 of 41967, Other and not yet classified: 2 of 41968, Human clinical research: 3 of 101968, Other and not yet classified: 7 of 101969, Human clinical research: 3 of 241969, Preclinical (animal, in vitro, computational): 3 of 241969, Other and not yet classified: 18 of 241970, Human clinical research: 3 of 211970, Preclinical (animal, in vitro, computational): 2 of 211970, Other and not yet classified: 16 of 211971, Human clinical research: 2 of 211971, Preclinical (animal, in vitro, computational): 4 of 211971, Other and not yet classified: 15 of 211972, Human clinical research: 4 of 271972, Preclinical (animal, in vitro, computational): 4 of 271972, Other and not yet classified: 19 of 271973, Human clinical research: 1 of 101973, Preclinical (animal, in vitro, computational): 1 of 101973, Reviews and meta-analyses: 1 of 101973, Other and not yet classified: 7 of 101974, Human clinical research: 4 of 181974, Preclinical (animal, in vitro, computational): 4 of 181974, Other and not yet classified: 10 of 181975, Human clinical research: 29 of 501975, Preclinical (animal, in vitro, computational): 12 of 501975, Other and not yet classified: 9 of 501976, Human clinical research: 21 of 501976, Preclinical (animal, in vitro, computational): 17 of 501976, Other and not yet classified: 12 of 501977, Human clinical research: 16 of 491977, Preclinical (animal, in vitro, computational): 21 of 491977, Other and not yet classified: 12 of 491978, Human clinical research: 10 of 421978, Preclinical (animal, in vitro, computational): 20 of 421978, Other and not yet classified: 12 of 421979, Human clinical research: 22 of 401979, Preclinical (animal, in vitro, computational): 11 of 401979, Other and not yet classified: 7 of 401980, Human clinical research: 13 of 501980, Preclinical (animal, in vitro, computational): 30 of 501980, Other and not yet classified: 7 of 501981, Human clinical research: 16 of 691981, Preclinical (animal, in vitro, computational): 48 of 691981, Other and not yet classified: 5 of 691982, Human clinical research: 28 of 831982, Preclinical (animal, in vitro, computational): 48 of 831982, Reviews and meta-analyses: 2 of 831982, Other and not yet classified: 5 of 831983, Human clinical research: 26 of 771983, Preclinical (animal, in vitro, computational): 38 of 771983, Reviews and meta-analyses: 2 of 771983, Other and not yet classified: 11 of 771984, Human clinical research: 24 of 951984, Preclinical (animal, in vitro, computational): 61 of 951984, Reviews and meta-analyses: 1 of 951984, Other and not yet classified: 9 of 951985, Human clinical research: 35 of 1031985, Preclinical (animal, in vitro, computational): 59 of 1031985, Reviews and meta-analyses: 3 of 1031985, Other and not yet classified: 6 of 1031986, Human clinical research: 21 of 621986, Preclinical (animal, in vitro, computational): 38 of 621986, Other and not yet classified: 3 of 621987, Human clinical research: 26 of 811987, Preclinical (animal, in vitro, computational): 53 of 811987, Other and not yet classified: 2 of 811988, Human clinical research: 18 of 691988, Preclinical (animal, in vitro, computational): 45 of 691988, Reviews and meta-analyses: 2 of 691988, Other and not yet classified: 4 of 691989, Human clinical research: 27 of 691989, Preclinical (animal, in vitro, computational): 32 of 691989, Other and not yet classified: 10 of 691990, Human clinical research: 24 of 701990, Preclinical (animal, in vitro, computational): 43 of 701990, Reviews and meta-analyses: 1 of 701990, Other and not yet classified: 2 of 701991, Human clinical research: 28 of 521991, Preclinical (animal, in vitro, computational): 21 of 521991, Other and not yet classified: 3 of 521992, Human clinical research: 27 of 551992, Preclinical (animal, in vitro, computational): 25 of 551992, Reviews and meta-analyses: 1 of 551992, Other and not yet classified: 2 of 551993, Human clinical research: 25 of 491993, Preclinical (animal, in vitro, computational): 22 of 491993, Reviews and meta-analyses: 2 of 491994, Human clinical research: 41 of 661994, Preclinical (animal, in vitro, computational): 23 of 661994, Other and not yet classified: 2 of 661995, Human clinical research: 22 of 361995, Preclinical (animal, in vitro, computational): 13 of 361995, Other and not yet classified: 1 of 361996, Human clinical research: 23 of 471996, Preclinical (animal, in vitro, computational): 20 of 471996, Other and not yet classified: 4 of 471997, Human clinical research: 28 of 411997, Preclinical (animal, in vitro, computational): 8 of 411997, Reviews and meta-analyses: 1 of 411997, Other and not yet classified: 4 of 411998, Human clinical research: 39 of 641998, Preclinical (animal, in vitro, computational): 20 of 641998, Reviews and meta-analyses: 1 of 641998, Other and not yet classified: 4 of 641999, Human clinical research: 26 of 481999, Preclinical (animal, in vitro, computational): 14 of 481999, Reviews and meta-analyses: 1 of 481999, Other and not yet classified: 7 of 482000, Human clinical research: 29 of 472000, Preclinical (animal, in vitro, computational): 16 of 472000, Other and not yet classified: 2 of 472001, Human clinical research: 27 of 362001, Preclinical (animal, in vitro, computational): 7 of 362001, Reviews and meta-analyses: 2 of 362002, Human clinical research: 25 of 452002, Preclinical (animal, in vitro, computational): 17 of 452002, Reviews and meta-analyses: 1 of 452002, Other and not yet classified: 2 of 452003, Human clinical research: 21 of 312003, Preclinical (animal, in vitro, computational): 6 of 312003, Reviews and meta-analyses: 3 of 312003, Other and not yet classified: 1 of 312004, Human clinical research: 30 of 532004, Preclinical (animal, in vitro, computational): 17 of 532004, Reviews and meta-analyses: 1 of 532004, Other and not yet classified: 5 of 532005, Human clinical research: 27 of 362005, Preclinical (animal, in vitro, computational): 7 of 362005, Reviews and meta-analyses: 2 of 362006, Human clinical research: 30 of 342006, Preclinical (animal, in vitro, computational): 2 of 342006, Reviews and meta-analyses: 2 of 342007, Human clinical research: 24 of 382007, Preclinical (animal, in vitro, computational): 13 of 382007, Reviews and meta-analyses: 1 of 382008, Human clinical research: 19 of 382008, Preclinical (animal, in vitro, computational): 9 of 382008, Reviews and meta-analyses: 3 of 382008, Other and not yet classified: 7 of 382009, Human clinical research: 24 of 392009, Preclinical (animal, in vitro, computational): 7 of 392009, Reviews and meta-analyses: 3 of 392009, Other and not yet classified: 5 of 392010, Human clinical research: 29 of 432010, Preclinical (animal, in vitro, computational): 5 of 432010, Reviews and meta-analyses: 5 of 432010, Other and not yet classified: 4 of 432011, Human clinical research: 17 of 292011, Preclinical (animal, in vitro, computational): 9 of 292011, Reviews and meta-analyses: 2 of 292011, Other and not yet classified: 1 of 292012, Human clinical research: 31 of 372012, Preclinical (animal, in vitro, computational): 3 of 372012, Reviews and meta-analyses: 2 of 372012, Other and not yet classified: 1 of 372013, Human clinical research: 30 of 462013, Preclinical (animal, in vitro, computational): 5 of 462013, Reviews and meta-analyses: 6 of 462013, Other and not yet classified: 5 of 462014, Human clinical research: 21 of 272014, Preclinical (animal, in vitro, computational): 2 of 272014, Reviews and meta-analyses: 3 of 272014, Other and not yet classified: 1 of 272015, Human clinical research: 29 of 412015, Preclinical (animal, in vitro, computational): 5 of 412015, Reviews and meta-analyses: 3 of 412015, Other and not yet classified: 4 of 412016, Human clinical research: 21 of 292016, Preclinical (animal, in vitro, computational): 4 of 292016, Reviews and meta-analyses: 1 of 292016, Other and not yet classified: 3 of 292017, Human clinical research: 27 of 362017, Preclinical (animal, in vitro, computational): 6 of 362017, Reviews and meta-analyses: 3 of 362018, Human clinical research: 27 of 332018, Preclinical (animal, in vitro, computational): 3 of 332018, Reviews and meta-analyses: 1 of 332018, Other and not yet classified: 2 of 332019, Human clinical research: 24 of 342019, Preclinical (animal, in vitro, computational): 3 of 342019, Reviews and meta-analyses: 2 of 342019, Other and not yet classified: 5 of 342020, Human clinical research: 33 of 482020, Preclinical (animal, in vitro, computational): 8 of 482020, Other and not yet classified: 7 of 482021, Human clinical research: 24 of 342021, Preclinical (animal, in vitro, computational): 6 of 342021, Reviews and meta-analyses: 1 of 342021, Other and not yet classified: 3 of 342022, Human clinical research: 31 of 392022, Preclinical (animal, in vitro, computational): 6 of 392022, Reviews and meta-analyses: 1 of 392022, Other and not yet classified: 1 of 392023, Human clinical research: 25 of 342023, Preclinical (animal, in vitro, computational): 6 of 342023, Other and not yet classified: 3 of 342024, Human clinical research: 13 of 222024, Preclinical (animal, in vitro, computational): 5 of 222024, Reviews and meta-analyses: 1 of 222024, Other and not yet classified: 3 of 222025, Human clinical research: 35 of 432025, Preclinical (animal, in vitro, computational): 2 of 432025, Other and not yet classified: 6 of 432026 (to date), Human clinical research: 26 of 332026 (to date), Preclinical (animal, in vitro, computational): 4 of 332026 (to date), Reviews and meta-analyses: 2 of 332026 (to date), Other and not yet classified: 1 of 33Human clinical researchPreclinical (animal, in vitro, computational)Reviews and meta-analysesOther and not yet classified05010015019541971198620012026*
Counted PubMed publications by year of first publication. * 2026 runs to November 1, 2026. A larger bar is more publications, not stronger evidence.
Show the data
YearHuman clinical researchPreclinical (animal, in vitro, computational)Reviews and meta-analysesOther and not yet classifiedTotal
195400066
195500011
195700011
195800033
195900011
196102024
196200011
1963100910
19640001111
196500033
196600033
196720024
1968300710
19693301824
19703201621
19712401521
19724401927
1973111710
19744401018
197529120950
1976211701250
1977162101249
1978102001242
197922110740
198013300750
198116480569
198228482583
1983263821177
198424611995
1985355936103
198621380362
198726530281
198818452469
1989273201069
199024431270
199128210352
199227251255
199325222049
199441230266
199522130136
199623200447
19972881441
199839201464
199926141748
200029160247
20012772036
200225171245
20032163131
200430171553
20052772036
20063022034
200724131038
20081993738
20092473539
20102955443
20111792129
20123132137
20133056546
20142123127
20152953441
20162141329
20172763036
20182731233
20192432534
20203380748
20212461334
20223161139
20232560334
20241351322
20253520643
2026 (to date)2642133

Study types

Animal study843
Observational human study560
Other clinical trial436
Not yet classified248
Case report216
Randomized controlled trial125
In vitro study98
Editorial, letter or other97
Review60
Meta-analysis7
Computational study4
Guideline or consensus3
Correction or retraction notice2
Systematic review2

Research areas

From MeSH major topics. A paper can be in several areas.

Endocrinology1,688
Neurological and mental health675
Immune system384
Reproductive and sexual health275
Metabolic health206
Cardiovascular154
Oncology150
Antimicrobial and infectious disease130
Musculoskeletal102
Dermatology97
Gastrointestinal58
Obesity and weight management39

Registered clinical trials

7 of 18 trials completed at least a year before the cutoff have neither posted results nor a linked results publication. A registration is not a result.

Completed: 19 · Unknown status: 6 · Active, not recruiting: 4 · Terminated: 4 · Recruiting: 3 · Withdrawn: 2 · Suspended: 1
Early phase 1: 6 · Phase not applicable: 17 · Phase 1: 4 · Phase 2: 4 · Phase 3: 3 · Phase 4: 5

TrialStatusPhaseStartedResults
Subclinical Primary Aldosteronism in Diabetes At-Risk for Kidney DiseaseNCT06190158 · 125 enrolledActive, not recruitingEarly phase 12024-05—
Study to Explore the Effect of Dapagliflozin and Stress in Adolescent and Adult Subjects With Type 1 Diabetes (T1D)NCT04234867 · 2 enrolledTerminatedPhase 12022-05—
Updated Diagnostic Cortisol Values for Adrenal InsufficiencyNCT05149638 · 90 enrolledRecruitingPhase not applicable2022-02—
Positron Emission Tomography (PET) Imaging of Cholesterol Trafficking: Clinical Evaluation of [18F]FNP-59 in Normal Human Subjects (Groups 2, 3 & 4)NCT04546126 · 24 enrolledRecruitingEarly phase 12021-11—
Defining the Mechanisms Underlying Adrenal Insufficiency in CirrhosisNCT04642391 · 76 enrolledCompletedPhase not applicable2021-08—
Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal WomenNCT04037605 · 5 enrolledActive, not recruitingEarly phase 12020-02—
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOSNCT03905603 · 144 enrolledUnknown statusEarly phase 12019-10—
Comparison of Intramuscular and Intravenous ACTH Stimulation Test in Normal VolunteersNCT03752190WithdrawnPhase 42019-07—
Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's DiseaseNCT03793114 · 200 enrolledActive, not recruitingPhase not applicable2018-09—
A Study to Assess the Efficacy and Safety of MNK-1411 in Duchenne Muscular DystrophyNCT03400852 · 44 enrolledTerminatedPhase 22018-07Posted
Effect of Longer-term Adrenal Suppression Using Low Dose Hydrocortisone on Androgen OverproductionNCT01422733WithdrawnEarly phase 12018-06—
A Novel Approach to Infantile SpasmsNCT03347526 · 394 enrolledSuspendedPhase 32018-04—
Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients?NCT03368066 · 100 enrolledCompletedPhase 32018-01Posted
Effect of Adrenocorticotropic Hormone on Vascular Endothelial Growth Factor Release in Children StudyNCT03709381 · 10 enrolledCompletedEarly phase 12017-10—
Hormonal Mechanisms of Sleep Restriction - Axis StudyNCT03142893 · 80 enrolledActive, not recruitingPhase 12017-05—
Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late AfternoonNCT03074123 · 20 enrolledCompletedPhase not applicable2017-04—
Prevalence of Adrenal Insufficiency in Kidney Transplanted Patients in Glucocorticoid TreatmentNCT03136562 · 60 enrolledCompletedPhase not applicable2017-03—
Salivary Free Cortisol Response to Cosyntropin Stimulation Test in Mitotane Treated PatientsNCT03083834 · 50 enrolledUnknown statusPhase not applicable2017-03—
Evaluation of the Effectiveness and Tolerance of Tetracosactide Synacthen® in the Treatment of Post Dural Puncture Headaches (ESYBRECHE)NCT02813655 · 46 enrolledTerminatedPhase 22016-10—
Mass Spectrometry Based Cutoffs for Cortisol After Stimulation TestsNCT02818660 · 232 enrolledCompletedPhase not applicable2016-05—
Stress and the Nervous SystemNCT02339506 · 23 enrolledCompletedPhase not applicable2015-04Posted
Adrenocorticotropic Hormone Stimulation in Postural Orthostatic Tachycardia Syndrome (POTS)NCT01764711 · 13 enrolledCompletedPhase not applicable2013-01Posted
NeSST2: The Development of a Noninvasive Short Synacthen TestNCT03514589 · 12 enrolledRecruitingPhase 22012-10—
Stress Biomarkers:Attaching Biological Meaning to Field Friendly Salivary MeasuresNCT01673087 · 256 enrolledCompletedPhase 12012-10—
Value of 25 mcg Cortrosyn Stimulation TestNCT01428336 · 22 enrolledCompletedPhase not applicable2011-09Posted
Difference in GC-induced Adrenal Insufficiency in RA Related to Polymorphisms in the Glucocorticoid Receptor GeneNCT01411046 · 106 enrolledUnknown statusPhase not applicable2011-04—
Influence of Synacthen Infusion on the Results of Adrenal Venous Sampling in Patient With Primary AldosteronismNCT02127840 · 40 enrolledUnknown statusPhase 42011-03—
Revival of Stem Cells in Addison's StudyNCT01371526 · 13 enrolledCompletedPhase 42010-09—
Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture HeadacheNCT02394457 · 29 enrolledCompletedPhase 42010-08Posted
The Adrenal Contribution to Androgen Production in Girls During PubertyNCT01062568 · 50 enrolledCompletedPhase 32010-02Posted
Optimization of the Evaluation of the Adrenal Function After Discontinuation of a Prolonged Therapy With CorticosteroidsNCT01053754 · 10 enrolledTerminatedPhase not applicable2010-01—
Mechanisms of Increased Androgen Production Among Women With Polycystic Ovary SyndromeNCT00989781 · 41 enrolledCompletedPhase not applicable2009-09Posted
Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac SurgeryNCT01839812 · 35 enrolledCompletedPhase 12009-03—
Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen TestNCT00851942 · 165 enrolledCompletedPhase 42008-09—
Treatment With Synthetic ACTH in High Risk Patients With Membranous NephropathyNCT00694863 · 20 enrolledCompletedPhase 22008-07—
Evaluation of Adrenal Androgens in Normal and Obese Girls After Suppression and StimulationNCT01421797 · 84 enrolledUnknown statusPhase not applicable2006-10—
Adrenal Functions in Autosomal Dominant Polycystic Kidney DiseaseNCT00598377 · 49 enrolledCompletedPhase not applicable2006-09—
Isolated ACTH Deficiency in Patients With Hashimoto ThyroiditisNCT00552487 · 62 enrolledCompletedPhase not applicable2005-10—
Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head InjuryNCT00006270 · 32 enrolledUnknown statusPhase not applicable1998-02—

Human trials and evidence reviews

Meta-analyses, systematic reviews and trials in people, newest first.

  1. Examining aldosterone plasma concentration alterations post-ACTH stimulation in healthy subjects: a systematic literature review and meta-analysis on ACTH's role in aldosterone secretion.

    Hormones (Athens, Greece) · July 25, 2024 · Meta-analysis · cited 5 times

    PMID 39052132 · DOI 10.1007/s42000-024-00583-6 · Reviews and meta-analyses

  2. 17-Hydroxyprogesterone Response to Standard Dose Synacthen Stimulation Test in CYP21A2 Heterozygous Carriers and Non-carriers in Symptomatic and Asymptomatic Groups: Meta-analyses

    Journal of clinical research in pediatric endocrinology · November 8, 2021 · Meta-analysis · cited 0 times · open access

    PMID 34743977 · DOI 10.4274/jcrpe.galenos.2021.2021.0184 · Reviews and meta-analyses

  3. A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children.

    Archives of disease in childhood · March 7, 2016 · Meta-analysis · cited 36 times

    PMID 26951687 · DOI 10.1136/archdischild-2015-308925 · Reviews and meta-analyses

  4. Treatment of infantile spasms.

    The Cochrane database of systematic reviews · June 5, 2013 · Meta-analysis · cited 274 times · open access

    PMID 23740534 · DOI 10.1002/14651858.cd001770.pub3 · Reviews and meta-analyses

  5. Drug therapy for preventing post-dural puncture headache.

    The Cochrane database of systematic reviews · February 28, 2013 · Meta-analysis · cited 72 times · open access

    PMID 23450533 · DOI 10.1002/14651858.cd001792.pub3 · Reviews and meta-analyses

  6. Corticotropin tests for hypothalamic-pituitary- adrenal insufficiency: a metaanalysis.

    The Journal of clinical endocrinology and metabolism · August 12, 2008 · Meta-analysis · cited 389 times · open access

    PMID 18697868 · DOI 10.1210/jc.2008-0710 · Reviews and meta-analyses

  7. Safety and efficacy of mometasone furoate aqueous nasal spray in children with allergic rhinitis: results of recent clinical trials.

    The Journal of allergy and clinical immunology · July 1, 2001 · Meta-analysis · cited 53 times

    PMID 11449207 · DOI 10.1067/mai.2001.115567 · Reviews and meta-analyses

  8. Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

    Intensive care medicine · September 21, 2017 · Systematic review · cited 371 times · open access

    PMID 28940011 · DOI 10.1007/s00134-017-4919-5 · Reviews and meta-analyses

  9. Drug therapy for treating post-dural puncture headache.

    The Cochrane database of systematic reviews · July 15, 2015 · Systematic review · cited 173 times · open access

    PMID 26176166 · DOI 10.1002/14651858.cd007887.pub3 · Reviews and meta-analyses

  10. Investigating a Mineralocorticoid Receptor Mediation of an Ultra-Short Feedback Loop Regulating Aldosterone Production in Humans.

    Clinical endocrinology · August 12, 2026 · Randomized controlled trial · cited 0 times · open access

    PMID 42581762 · DOI 10.1111/cen.70189 · Human clinical research

Most cited

By OpenAlex citation count. Citations measure attention, not quality or correctness.

  1. Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis.

    Psychosomatic medicine · March 1, 1999 · Other clinical trial · cited 1,890 times

    PMID 10204967 · DOI 10.1097/00006842-199903000-00006 · Human clinical research

  2. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline.

    The Journal of clinical endocrinology and metabolism · June 13, 2008 · Guideline or consensus · cited 1,560 times · open access

    PMID 18552288 · DOI 10.1210/jc.2008-0104 · Commentary and other

  3. Corticosteroid insufficiency in acutely ill patients.

    The New England journal of medicine · February 1, 2003 · Review · cited 1,044 times

    PMID 12594318 · DOI 10.1056/nejmra020529 · Reviews and meta-analyses

  4. A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin.

    JAMA · February 1, 2000 · Observational human study · cited 1,008 times

    PMID 10697064 · DOI 10.1001/jama.283.8.1038 · Human clinical research

  5. Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse.

    The American journal of psychiatry · April 1, 2001 · Other clinical trial · cited 745 times

    PMID 11282691 · DOI 10.1176/appi.ajp.158.4.575 · Human clinical research

Latest publications

  1. Biological response stability of refrigerated cosacthen after opening and non-hormonal effects of ACTH stimulation testing in healthy dogs.

    Topics in companion animal medicine · October 9, 2026 · Other clinical trial · cited 0 times · open access

    PMID 42854896 · DOI 10.1016/j.tcam.2026.101106 · Human clinical research

  2. Comparison of Salivary Cortisol, Cortisone, and Dexamethasone with Serum Measurements Across Dynamic Adrenal Testing.

    The Journal of clinical endocrinology and metabolism · September 26, 2026 · Observational human study · cited 0 times

    PMID 42791226 · DOI 10.1210/clinem/dgag393 · Human clinical research

  3. Adult nonclassic P450 oxidoreductase deficiency diagnosed 11 years after reproductive-endocrine suspicion.

    JCEM case reports · September 11, 2026 · Case report · cited 0 times · open access

    PMID 42729616 · DOI 10.1210/jcemcr/luag267 · Human clinical research

  4. Limited Diagnostic Utility of Cortisol and Growth Hormone Levels Obtained during Hypoglycemia in Children.

    Hormone research in paediatrics · September 7, 2026 · Observational human study · cited 0 times · open access

    PMID 42704757 · DOI 10.1159/hrp/adaag003 · Human clinical research

  5. The utility of cosyntropin stimulation test in the assessment of adrenal function after unilateral adrenalectomy.

    Surgery · September 1, 2026 · Observational human study · cited 0 times · open access

    PMID 42816228 · DOI 10.1016/j.surg.2026.110585 · Human clinical research

  6. Coexisting mild autonomous cortisol secretion and isolated adrenocorticotropic hormone deficiency in a patient with an adrenal incidentaloma.

    JCEM case reports · August 24, 2026 · Case report · cited 0 times · open access

    PMID 42634837 · DOI 10.1210/jcemcr/luag229 · Human clinical research

  7. Liver cirrhosis is associated with altered glucocorticoid metabolism related to disease severity.

    Journal of internal medicine · August 14, 2026 · Observational human study · cited 0 times · open access

    PMID 42598738 · DOI 10.1111/joim.70149 · Human clinical research

  8. Investigating a Mineralocorticoid Receptor Mediation of an Ultra-Short Feedback Loop Regulating Aldosterone Production in Humans.

    Clinical endocrinology · August 12, 2026 · Randomized controlled trial · cited 0 times · open access

    PMID 42581762 · DOI 10.1111/cen.70189 · Human clinical research

  9. Adrenal insufficiency diagnosis: new approaches to indeterminate baseline cortisol.

    Current opinion in endocrinology, diabetes, and obesity · August 5, 2026 · Review · cited 0 times

    PMID 42559695 · DOI 10.1097/med.0000000000000969 · Reviews and meta-analyses

  10. Timing of 17-hydroxyprogesterone measurement during the standard-dose Synacthen test in pediatric patients evaluated for non-classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

    Archives of endocrinology and metabolism · July 31, 2026 · Observational human study · cited 0 times · open access

    PMID 42536762 · DOI 10.20945/2359-4292-2026-0081 · Human clinical research

Browse all 2,701 publications in the dashboard

How this is counted

PubMed records matched by the names below, counted when the peptide is in the title, indexed by MeSH, or confirmed from the abstract. The exact query can be rerun on Europe PMC. Methodology

Search terms: ACTH 1-24; Actholain; Cortrosyn; Cosyntropin; Synacthen; Tetracosactid; Tetracosactida; Tetracosactide; Tetracosactidum; Tetracosactrin; Vicotrope

((TITLE_ABS:"ACTH 1-24" OR CHEM:"ACTH 1-24" OR TITLE_ABS:"ACTH1-24" OR CHEM:"ACTH1-24") OR (TITLE_ABS:"Actholain" OR CHEM:"Actholain") OR (TITLE_ABS:"Cortrosyn" OR CHEM:"Cortrosyn") OR (TITLE_ABS:"Cosyntropin" OR CHEM:"Cosyntropin") OR (TITLE_ABS:"Synacthen" OR CHEM:"Synacthen") OR (TITLE_ABS:"Tetracosactid" OR CHEM:"Tetracosactid") OR (TITLE_ABS:"Tetracosactida" OR CHEM:"Tetracosactida") OR (TITLE_ABS:"Tetracosactide" OR CHEM:"Tetracosactide") OR (TITLE_ABS:"Tetracosactidum" OR CHEM:"Tetracosactidum") OR (TITLE_ABS:"Tetracosactrin" OR CHEM:"Tetracosactrin") OR (TITLE_ABS:"Vicotrope" OR CHEM:"Vicotrope")) AND SRC:MED

Cite this page

Peptide Library. (2026, November 2). Cosyntropin research statistics (Version weekly-2026-11-01) [Statistic]. Peptide Library. https://peptidelibrary.app/research/peptides/cosyntropin