Peptide LibraryResearch statistics
Cetrorelix research: publications and trials
At a glance
Publications, all years
759
Since 1990
Publications in 2026 so far
12
Through November 1, 2026
Human clinical research
46.1%
348 of 755 classified
Registered clinical trials
92
ClinicalTrials.gov
Randomized controlled trials
119
Publications reporting an RCT in people
Systematic reviews and meta-analyses
8
Preclinical studies
42.0%
225 animal · 88 in vitro · 4 computational
Records that only mention it
48
Not counted above
Status in the library: FDA-approved. 4 publications are not yet classified by study type.
What to keep in mind
- Some completed trials have neither posted results nor a linked results publication.
Publications by year
Cetrorelix publications by year and evidence
Show the data
| Year | Human clinical research | Preclinical (animal, in vitro, computational) | Reviews and meta-analyses | Other and not yet classified | Total |
|---|---|---|---|---|---|
| 1990 | 0 | 7 | 0 | 0 | 7 |
| 1991 | 0 | 5 | 0 | 0 | 5 |
| 1992 | 1 | 9 | 1 | 0 | 11 |
| 1993 | 1 | 9 | 0 | 0 | 10 |
| 1994 | 8 | 11 | 0 | 3 | 22 |
| 1995 | 4 | 5 | 1 | 0 | 10 |
| 1996 | 3 | 3 | 0 | 0 | 6 |
| 1997 | 4 | 8 | 1 | 0 | 13 |
| 1998 | 5 | 12 | 3 | 1 | 21 |
| 1999 | 8 | 4 | 1 | 1 | 14 |
| 2000 | 12 | 16 | 3 | 3 | 34 |
| 2001 | 13 | 16 | 8 | 1 | 38 |
| 2002 | 11 | 13 | 8 | 1 | 33 |
| 2003 | 18 | 11 | 6 | 2 | 37 |
| 2004 | 16 | 14 | 5 | 0 | 35 |
| 2005 | 18 | 14 | 8 | 0 | 40 |
| 2006 | 25 | 8 | 11 | 0 | 44 |
| 2007 | 17 | 5 | 2 | 0 | 24 |
| 2008 | 25 | 14 | 0 | 4 | 43 |
| 2009 | 15 | 13 | 2 | 1 | 31 |
| 2010 | 9 | 10 | 1 | 2 | 22 |
| 2011 | 13 | 12 | 3 | 0 | 28 |
| 2012 | 11 | 14 | 1 | 2 | 28 |
| 2013 | 12 | 4 | 0 | 1 | 17 |
| 2014 | 13 | 7 | 0 | 1 | 21 |
| 2015 | 11 | 8 | 0 | 0 | 19 |
| 2016 | 12 | 6 | 0 | 0 | 18 |
| 2017 | 13 | 5 | 0 | 0 | 18 |
| 2018 | 8 | 3 | 1 | 0 | 12 |
| 2019 | 7 | 9 | 0 | 0 | 16 |
| 2020 | 9 | 9 | 0 | 0 | 18 |
| 2021 | 8 | 7 | 0 | 0 | 15 |
| 2022 | 3 | 6 | 1 | 0 | 10 |
| 2023 | 5 | 3 | 1 | 0 | 9 |
| 2024 | 2 | 4 | 1 | 0 | 7 |
| 2025 | 3 | 7 | 1 | 0 | 11 |
| 2026 (to date) | 5 | 6 | 1 | 0 | 12 |
Study types
| Animal study | 225 |
|---|---|
| Observational human study | 121 |
| Randomized controlled trial | 119 |
| Other clinical trial | 89 |
| In vitro study | 88 |
| Review | 63 |
| Case report | 19 |
| Editorial, letter or other | 19 |
| Meta-analysis | 7 |
| Computational study | 4 |
| Not yet classified | 4 |
| Systematic review | 1 |
Research areas
From MeSH major topics. A paper can be in several areas.
| Reproductive and sexual health | 566 |
|---|---|
| Endocrinology | 391 |
| Oncology | 144 |
| Neurological and mental health | 49 |
| Dermatology | 13 |
| Immune system | 12 |
| Metabolic health | 12 |
| Gastrointestinal | 9 |
| Cardiovascular | 7 |
| Musculoskeletal | 6 |
| Obesity and weight management | 6 |
| Tissue repair | 5 |
Registered clinical trials
27 of 51 trials completed at least a year before the cutoff have neither posted results nor a linked results publication. A registration is not a result.
Completed: 54 · Unknown status: 25 · Terminated: 5 · Not yet recruiting: 4 · Recruiting: 2 · Active, not recruiting: 1 · Withdrawn: 1
Early phase 1: 2 · Phase not applicable: 30 · Phase 1 / Phase 2: 4 · Phase 2: 7 · Phase 2 / Phase 3: 2 · Phase 3: 19 · Phase 4: 28
The 50 most recently started of 92 trials.
Human trials and evidence reviews
Meta-analyses, systematic reviews and trials in people, newest first.
- Efficacy of GnRH antagonists in the treatment of uterine fibroids: a meta-analysis.
Archives of gynecology and obstetrics · January 16, 2025 · Meta-analysis · cited 13 times · open access
PMID 39821450 · DOI 10.1007/s00404-025-07932-9 · Reviews and meta-analyses
- Single dose GnRH agonist administration in the luteal phase of assisted reproduction cycles: is the effect dependent on the type of GnRH analogue used for pituitary suppression?
Reproductive biomedicine online · November 10, 2009 · Meta-analysis · cited 16 times · open access
PMID 20159003 · DOI 10.1016/j.rbmo.2009.10.022 · Reviews and meta-analyses
- Effects and clinical significance of GnRH antagonist administration for IUI timing in FSH superovulated cycles: a meta-analysis.
Fertility and sterility · October 23, 2007 · Meta-analysis · cited 42 times · open access
PMID 17936285 · DOI 10.1016/j.fertnstert.2007.06.064 · Reviews and meta-analyses
- GnRH-antagonists in ovarian stimulation for IVF in patients with poor response to gonadotrophins, polycystic ovary syndrome, and risk of ovarian hyperstimulation: a meta-analysis.
Reproductive biomedicine online · November 1, 2006 · Meta-analysis · cited 158 times · open access
PMID 17169171 · DOI 10.1016/s1472-6483(10)60652-9 · Reviews and meta-analyses
- Gonadotrophin-releasing hormone antagonists for assisted conception.
The Cochrane database of systematic reviews · July 19, 2006 · Meta-analysis · cited 247 times
PMID 16855976 · DOI 10.1002/14651858.cd001750.pub2 · Reviews and meta-analyses
- Safety aspects of gonadotrophin-releasing hormone antagonists in ovarian stimulation procedures: ovarian hyperstimulation syndrome and health of children born.
Reproductive biomedicine online · January 1, 2002 · Meta-analysis · cited 12 times
PMID 12537784 · DOI 10.1016/s1472-6483(11)60219-8 · Reviews and meta-analyses
- Use of GnRH antagonists in ovarian stimulation for assisted reproductive technologies compared to the long protocol. Meta-analysis.
Archives of gynecology and obstetrics · November 1, 2001 · Meta-analysis · cited 153 times
PMID 11789740 · DOI 10.1007/s00404-001-0267-2 · Reviews and meta-analyses
- Gonadotrophin-releasing hormone antagonists for assisted conception.
The Cochrane database of systematic reviews · January 1, 2001 · Systematic review · cited 67 times
PMID 11687120 · DOI 10.1002/14651858.cd001750 · Reviews and meta-analyses
- Cocktail treatment by GnRH-antagonist, letrozole, and mifepristone for the prevention of ovarian hyperstimulation syndrome: a prospective randomized trial.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology · October 16, 2023 · Randomized controlled trial · cited 2 times · open access
PMID 37844908 · DOI 10.1080/09513590.2023.2269281 · Human clinical research
- Medroxyprogesterone Acetate versus Gonadotropin-Releasing Hormone Antagonist for the Prevention of Premature Luteinizing Hormone Surge in hyper-responder women undergoing controlled ovarian stimulation for IVF/ICSI Cycles.
JBRA assisted reproduction · March 30, 2023 · Randomized controlled trial · cited 5 times · open access
PMID 35621299 · DOI 10.5935/1518-0557.20220006 · Human clinical research
Most cited
By OpenAlex citation count. Citations measure attention, not quality or correctness.
- Premature luteinization during gonadotropin-releasing hormone antagonist cycles and its relationship with in vitro fertilization outcome.
Fertility and sterility · December 1, 2003 · Other clinical trial · cited 343 times · open access
PMID 14667881 · DOI 10.1016/j.fertnstert.2003.07.002 · Human clinical research
- Ovarian stimulation with HMG: results of a prospective randomized phase III European study comparing the luteinizing hormone-releasing hormone (LHRH)-antagonist cetrorelix and the LHRH-agonist buserelin. European Cetrorelix Study Group.
Human reproduction (Oxford, England) · March 1, 2000 · Randomized controlled trial · cited 312 times
PMID 10686191 · DOI 10.1093/humrep/15.3.526 · Human clinical research
- Suppression of the endogenous luteinizing hormone surge by the gonadotrophin-releasing hormone antagonist Cetrorelix during ovarian stimulation.
Human reproduction (Oxford, England) · May 1, 1994 · Other clinical trial · cited 310 times
PMID 7929723 · DOI 10.1093/oxfordjournals.humrep.a138597 · Human clinical research
- Prospective, randomized, controlled study of in vitro fertilization-embryo transfer with a single dose of a luteinizing hormone-releasing hormone (LH-RH) antagonist (cetrorelix) or a depot formula of an LH-RH agonist (triptorelin).
Fertility and sterility · February 1, 2000 · Randomized controlled trial · cited 257 times · open access
PMID 10685535 · DOI 10.1016/s0015-0282(99)00524-5 · Human clinical research
- Gonadotrophin-releasing hormone antagonists for assisted conception.
The Cochrane database of systematic reviews · July 19, 2006 · Meta-analysis · cited 247 times
PMID 16855976 · DOI 10.1002/14651858.cd001750.pub2 · Reviews and meta-analyses
Latest publications
- Oral gonadotropin-releasing hormone antagonists versus injectable cetrorelix for luteinizing hormone surge prevention in donor in vitro fertilization cycles: A retrospective cohort study of efficacy, embryology, and stimulation dynamics.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · October 19, 2026 · Observational human study · cited 0 times · open access
PMID 42897926 · DOI 10.1002/ijgo.71408 · Human clinical research
- <i>Radix Bupleuri Chinensis</i> Extract Ameliorates Doxorubicin-Induced Spermatogenic Dysfunction: Involvement of the GnRHR Signaling Pathway and Taurine Biosynthesis.
Pharmaceuticals (Basel, Switzerland) · August 13, 2026 · Animal study · cited 0 times · open access
PMID 42653776 · DOI 10.3390/ph19081280 · Animal studies
- Evaluating progestin-primed and GnRH antagonist ovarian stimulation protocols in PGT-A cycles: implications for clinical practice.
BMC pregnancy and childbirth · June 30, 2026 · Observational human study · cited 0 times · open access
PMID 42380839 · DOI 10.1186/s12884-026-09540-0 · Human clinical research
- Comparison of Chitosan-Poloxamer Nanoparticles and Poloxamer-based In-Situ Forming Gel for Nose-to-Brain Delivery of Cetrorelix: In Vitro and Pharmacokinetic Studies in Rats.
AAPS PharmSciTech · June 4, 2026 · Animal study · cited 0 times
PMID 42243608 · DOI 10.1208/s12249-026-03430-6 · Animal studies
- GnRH Agonists and Antagonists in IVF/ICSI Cycles of PCOS Women: A Network Meta-Analysis.
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP · May 1, 2026 · Review · cited 0 times · open access
PMID 42152207 · DOI 10.29271/jcpsp.2026.05.654 · Reviews and meta-analyses
- Efficacy and safety of different cetrorelix doses in the luteal phase for preventing ovarian hyperstimulation syndrome: A cross-sectional study.
International journal of reproductive biomedicine · April 1, 2026 · Observational human study · cited 0 times · open access
PMID 42312112 · DOI 10.18502/ijrm.v24i4.21173 · Human clinical research
- Medroxyprogesterone acetate vs. GnRH antagonist for preventing premature LH surge during ovarian stimulation in assisted reproductive technology: a retrospective cohort study.
Frontiers in reproductive health · March 19, 2026 · Observational human study · cited 0 times · open access
PMID 41939000 · DOI 10.3389/frph.2026.1793207 · Human clinical research
- A new cetrorelix-based estrogen-free ovarian synchronization protocol for fixed-time artificial insemination in beef cattle.
Theriogenology · March 17, 2026 · Animal study · cited 0 times · open access
PMID 41864162 · DOI 10.1016/j.theriogenology.2026.117904 · Animal studies
- Cetrorelix suppresses the dominant follicle and synchronizes follicular waves and ovulation in cattle†.
Biology of reproduction · March 1, 2026 · Animal study · cited 1 times · open access
PMID 41395811 · DOI 10.1093/biolre/ioaf276 · Animal studies
- Hydrogel and oleogel formulation of the decapeptide cetrorelix acetate for nasal administration.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · February 19, 2026 · Animal study · cited 2 times · open access
PMID 41722737 · DOI 10.1016/j.ejps.2026.107482 · Animal studies
How this is counted
PubMed records matched by the names below, counted when the peptide is in the title, indexed by MeSH, or confirmed from the abstract. The exact query can be rerun on Europe PMC. Methodology
Search terms: Cetrorelix; Cetrorelixum; Cetrotide; SB-075
((TITLE_ABS:"Cetrorelix" OR CHEM:"Cetrorelix") OR (TITLE_ABS:"Cetrorelixum" OR CHEM:"Cetrorelixum") OR (TITLE_ABS:"Cetrotide" OR CHEM:"Cetrotide") OR (TITLE_ABS:"SB-075" OR CHEM:"SB-075" OR TITLE_ABS:"SB075" OR CHEM:"SB075")) AND SRC:MED
Cite this page
Peptide Library. (2026, November 2). Cetrorelix research statistics (Version weekly-2026-11-01) [Statistic]. Peptide Library. https://peptidelibrary.app/research/peptides/cetrorelix