Dipeptide Diaminobutyroyl Benzylamide Diacetate
CosmeticCosmetic nicotinic antagonist mimeticExperimental
Waglerin-1–inspired tripeptide used in cosmetics to reduce expression-line appearance. Topical cosmetic active, not an FDA drug.
For research use only.
Key Facts
- CAS
- 823202-99-9
- Molecular Weight (MW)
- —
- Half-life
- Topical; systemic PK not established
- Unit
- mcg
- Administration Route
- Topical
- Frequency
- —
- Last updated
- 8/23/2026
- Targets
- Muscle nAChR (model systems)
Overview
Waglerin-1–inspired tripeptide used in cosmetics to reduce expression-line appearance. Topical cosmetic active, not an FDA drug.
Protocol
- Dosage Range
- Per cosmetic formulation
- Frequency
- —
- Cycle
- —
- Administration Route
- Topical
- Reconstitution Guide
- —
Science
Mechanism of Action
Reversible antagonist-like activity at the muscle nicotinic acetylcholine receptor in vitro, intended to reduce microcontraction of expression muscles when used topically.
Targets
Muscle nAChR (model systems)
Studies
- SYN-AKE cosmetic peptide literature— Journal/year not available
Benefits
Topical expression-line cosmetics
Potential Side Effects
- Irritation
- Redness
References
- PubChem SYN-AKEExternal link · Year —