Myristoyl Pentapeptide-17
Myristoyl Pentapeptide-17 is a cosmetic lash and brow peptide. Attachment of a myristoyl fatty acid chain increases lipophilicity and is intended to improve penetration into the follicular unit. The peptide is reported by suppliers to influence keratin gene expression in the hair follicle.
For research use only.
Key Facts
- CAS
- 959610-30-1
- Molecular Weight (MW)
- 796.1 g/mol
- Half-life
- —
- FDA status
- Not Approved
- Administration Route
- topical
- Frequency
- —
- Last updated
- Aug 30, 2026
- Reviewed
- Aug 30, 2026
Research summary
Lipidated pentapeptide used in eyelash and eyebrow conditioning products. Regulated as a cosmetic ingredient; not FDA-approved as a drug and not equivalent to prostaglandin analog lash treatments.
Peptide Library's Myristoyl Pentapeptide-17 profile summarises 4 cited studies listed in the Science section, the compound's regulatory status, and research-protocol parameters reported for it. It is a research reference, not medical advice.
Protocol
- Dosage Range
- —
- Frequency
- —
- Cycle
- —
- Administration Route
- topical
- Reconstitution Guide
- —
Sequence & molecular data
| Molecular formula | C41H81N9O6 |
|---|---|
| Molecular weight | 796.1 g/mol |
| CAS number | 959610-30-1 |
| PubChem CID | 127264611 |
Identifiers link to the public PubChem, FDA Substance Registration (UNII), ChEMBL and DrugBank records for the same entity.
Science
Mechanism of Action
Attachment of a myristoyl fatty acid chain increases lipophilicity and is intended to improve penetration into the follicular unit. The peptide is reported by suppliers to influence keratin gene expression in the hair follicle. Published independent evidence is limited, and its mechanism is entirely distinct from the prostaglandin F2-alpha analogs used in prescription lash products.
Studies
- Topical peptides as cosmeceuticals (class-level)
- Skin ageing and topical rejuvenation strategies (class-level)
- Open clinical trial evaluating the efficacy of a novel eyelash growth enhancer with peptides and glycosaminoglycans (class-level evidence)
- Prostaglandin analogues in cosmetic products formulated for eyelash lengthening (class-level evidence)
Regulatory & research status
Myristoyl Pentapeptide-17 is not an FDA-approved product. It is sold for laboratory research and has no approved medical use.
| FDA status | Not Approved |
|---|---|
| Research status | Research-only compound; no approval pathway listed |
| Availability | OTC / Supplement |
| WADA (sport) | Unknown / Not Listed |
| Library classification | Research-Only |
Benefits
—
Potential Side Effects
No side effects listed yet for this entry.
Storage & stability
Lyophilized (freeze-dried) peptide powder is far more stable than the reconstituted solution. Keep sealed vials cold, dry and away from light; long-term storage is typically frozen, with short-term refrigeration for vials in use.
Once reconstituted in bacteriostatic water, keep the solution refrigerated, avoid repeated freeze–thaw cycles and agitation, and label the vial with the reconstitution date and concentration. Discard any solution that turns cloudy or shows particulates.
Degradation rates differ by sequence: peptides containing methionine, cysteine, asparagine or glutamine are more prone to oxidation and deamidation, so shelf life after reconstitution is compound-specific rather than universal.
Cosmetic peptides in this library are formulated into topical products; follow the product label rather than the reconstitution guidance above.
Read the full guide: how to store peptides before and after reconstitution →
Source: Manning MC, Chou DK, Murphy BM, Payne RW, Katayama DS. Stability of protein pharmaceuticals: an update. Pharm Res. 2010;27(4):544–575. (PMID 20143256). General guidance for research handling; not product-specific instructions.
Myristoyl Pentapeptide-17: frequently asked questions
What is Myristoyl Pentapeptide-17?
Lipidated pentapeptide used in eyelash and eyebrow conditioning products. Regulated as a cosmetic ingredient; not FDA-approved as a drug and not equivalent to prostaglandin analog lash treatments.
How does Myristoyl Pentapeptide-17 work?
Attachment of a myristoyl fatty acid chain increases lipophilicity and is intended to improve penetration into the follicular unit. The peptide is reported by suppliers to influence keratin gene expression in the hair follicle.
Is Myristoyl Pentapeptide-17 FDA approved?
No. Myristoyl Pentapeptide-17 is not approved by the FDA for any indication and is categorised as otc / supplement. It has not been reviewed for safety or efficacy as a medicine, and published research should be read as investigation rather than established use.
What peptides are similar to Myristoyl Pentapeptide-17?
Compounds most often compared with Myristoyl Pentapeptide-17 include Acetyl Tetrapeptide-3, Biotinoyl Tripeptide-1, Decapeptide-12 and Palmitoyl Hexapeptide-12. They are grouped by shared mechanism or research area rather than by equivalence, and their regulatory status and evidence base differ.
References
- Class-level evidence — Topical peptides as cosmeceuticals. Indian J Dermatol Venereol Leprol, 2017External reference
- Class-level evidence — Skin ageing and topical rejuvenation strategies. Br J Dermatol, 2023External reference
- Class-level evidence — Open clinical trial evaluating the efficacy of a novel eyelash growth enhancer with peptides and glycosaminoglycans — J Cosmet Dermatol, 2024External reference
- Class-level evidence — Prostaglandin analogues in cosmetic products formulated for eyelash lengthening — Ann Pharm Fr, 2026External reference
Related research, comparisons & guides
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Compiled by Peptide Library Editorial · Reviewed Aug 30, 2026 · Updated Aug 30, 2026 · Version 1
This Myristoyl Pentapeptide-17 profile is compiled from published literature (4 cited studies linked above), public regulatory records and chemical registries. It describes what research reports; it is not medical advice, and nothing here is a dosing recommendation for humans. Peptide Library does not sell peptides. Editorial policy · How profiles are compiled · Report an error
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