Glutathione
CosmeticEndogenous Tripeptide / Antioxidant
Endogenous tripeptide antioxidant (GSH) central to cellular redox balance and detoxification; widely researched for oxidative stress and liver support.
For research use only.
Key Facts
- CAS
- 70-18-8
- Molecular Weight (MW)
- 307.32 g/mol
- Half-life
- ~1.5 hours (IV); oral bioavailability limited
- Unit
- mg
- Administration Route
- Oral, Subcutaneous, Intramuscular, or IV
- Frequency
- 1-3x weekly (injectable) or daily (oral)
- Last updated
- 2/21/2026
- Targets
- Reactive oxygen species (ROS)Glutathione peroxidase system
Overview
Endogenous tripeptide antioxidant (GSH) central to cellular redox balance and detoxification; widely researched for oxidative stress and liver support.
Protocol
- Dosage Range
- 250-2000 mg depending on route
- Frequency
- 1-3x weekly (injectable) or daily (oral)
- Cycle
- 4-12 weeks common; varies by research context
- Administration Route
- Oral, Subcutaneous, Intramuscular, or IV
- Reconstitution Guide
- Commonly reconstituted with bacteriostatic water for research use
May vary by vendor concentration and protocol.
Science
Mechanism of Action
Acts as primary intracellular antioxidant; neutralizes ROS, supports phase II liver detoxification, regenerates vitamins C and E.
Targets
Reactive oxygen species (ROS)Glutathione peroxidase system
Studies
- โ Journal/year not available
- โ Journal/year not available
- โ Journal/year not available
Benefits
Powerful intracellular antioxidantSupports liver detoxification pathwaysMay improve skin brightness (cosmetic use)Supports immune functionMitochondrial protectionReduces oxidative stress
Potential Side Effects
- Injection site irritation
- GI discomfort (oral)
- Rare bronchospasm (IV use)
- Headache
References
- PubChem CID 124886External link ยท Year โ
- NIH antioxidant research overviewExternal link ยท Year โ