Key Facts
- CAS
- 128270-60-0
- Molecular Weight (MW)
- 2180.3 g/mol
- Half-life
- ~25 minutes (normal renal function)
- Unit
- mcg
- Administration Route
- Intravenous
- Frequency
- Continuous IV infusion during procedure
- Last updated
- 2/17/2026
- Targets
- Thrombin
Overview
—
Protocol
- Dosage Range
- 0.75 mg/kg bolus followed by 1.75 mg/kg/hour infusion
- Frequency
- Continuous IV infusion during procedure
- Cycle
- Per procedure
- Administration Route
- Intravenous
- Reconstitution Guide
- Reconstitute with sterile water for injection per package insert
Science
Mechanism of Action
Binds catalytic site and exosite of thrombin, inhibits clotting.
Targets
Thrombin
Studies
- — Journal/year not available
Benefits
Anticoagulation during PCIAlternative for HIT
Potential Side Effects
- Bleeding
- Thrombocytopenia
References
- FDA Label - AngiomaxExternal link · Year —