Semaglutide & Tirzepatide

GLP-1/MetabolicWeight-Loss / Metabolic

Incretin-based therapies improving satiety and glycemic control; tirzepatide also activates GIP.

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For research use only.

Key Facts

CAS
Molecular Weight (MW)
Half-life
Unit
mg
Administration Route
Subcutaneous
Frequency
1× weekly
Last updated
12/14/2025
Targets
GLP-1 receptor (both)GIP receptor (tirzepatide)

Overview

Incretin-based therapies improving satiety and glycemic control; tirzepatide also activates GIP.

Protocol

Dosage Range
Semaglutide: 0.25→2.4 mg weekly; Tirzepatide: 2.5→10–15 mg weekly (titrate)
Frequency
1× weekly
Cycle
Long-term use for obesity/diabetes; reassess periodically
Administration Route
Subcutaneous
Reconstitution Guide

Science

Mechanism of Action

Incretin-based therapies improving satiety and glycemic control; tirzepatide also activates GIP.

Targets

GLP-1 receptor (both)GIP receptor (tirzepatide)

Studies are being curated for this entry.

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Benefits

Significant weight lossImproved glycemic markersAppetite suppression

Potential Side Effects

  • Nausea
  • Vomiting
  • Diarrhea/constipation
  • Possible lean mass loss without resistance training

References

References coming soon.

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