Human Chorionic Gonadotropin (hCG)

Endogenous Glycoprotein Hormone / FDA-approved prescription biologic (indication-specific)

Human chorionic gonadotropin is a placental glycoprotein hormone and prescription biologic that acts as an LH receptor agonist, used in indication-specific fertility and gonadal function protocols.

Calculate Dose

For research use only.

Key Facts

CAS: —
Molecular Weight (MW): Variable glycoprotein; approximately 36.7 to 38 kDa depending on glycosylation/source
Half-life: ~24-36 hours biological half life (route and product dependent)
Unit: IU
Administration Route: Intramuscular; some products/routes vary by labeling and clinical context
Frequency: Protocol dependent
Last updated: 3/10/2026
Targets: LH/CG receptor

Overview

Human chorionic gonadotropin is a placental glycoprotein hormone and prescription biologic that acts as an LH receptor agonist, used in indication-specific fertility and gonadal function protocols.

Protocol

Dosage Range: Common labeled doses range from 500 to 10000 USP units depending on indication
Frequency: Protocol dependent
Cycle: Use only per FDA labeling / prescriber direction
Administration Route: Intramuscular; some products/routes vary by labeling and clinical context
Reconstitution Guide: Reconstitute only per product labeling with supplied diluent; store as directed after reconstitution

Science

Mechanism of Action

Acts as an LH receptor agonist to stimulate testicular testosterone production in males and trigger final follicular maturation/ovulation in female fertility protocols.

Targets

LH/CG receptor

Studies

— Journal/year not available
— Journal/year not available
— Journal/year not available

Benefits

Supports testosterone production in appropriate male medical contextsUsed in selected cases of hypogonadotropic hypogonadismUsed in fertility protocols for ovulation triggeringUsed in selected pediatric cryptorchidism protocols