Human Chorionic Gonadotropin (hCG)

FDA-approved glycoprotein hormoneEstablished

FDA-approved LH-analog glycoprotein for ovulation induction and selected male hypogonadism uses. WADA prohibits hCG in males at all times (S2). Not approved for weight loss.

Calculate Dose

For research use only.

Key Facts

CAS: 9002-61-3
Molecular Weight (MW): ~36.7 kDa glycoprotein
Half-life: ~24-36 hours biological half life (route and product dependent)
Unit: IU
Administration Route: Intramuscular; some products/routes vary by labeling and clinical context
Frequency: Protocol dependent
Last updated: 8/23/2026
Targets: LHCGR

Overview

FDA-approved LH-analog glycoprotein for ovulation induction and selected male hypogonadism uses. WADA prohibits hCG in males at all times (S2). Not approved for weight loss.

Protocol

Dosage Range: Common labeled doses range from 500 to 10000 USP units depending on indication
Frequency: Protocol dependent
Cycle: Use only per FDA labeling / prescriber direction
Administration Route: Intramuscular; some products/routes vary by labeling and clinical context
Reconstitution Guide: Reconstitute only per product labeling with supplied diluent; store as directed after reconstitution

Science

Mechanism of Action

Binds LH/hCG receptors to trigger ovulation in women and stimulate Leydig-cell testosterone in men. Subunit structure is a heterodimeric glycoprotein.