BAM15

Fat LossSmall Molecule / Metabolic (Mitochondrial Uncoupler)Experimental

BAM15 is a synthetic small-molecule mitochondrial protonophore uncoupler used as a research tool to uncouple oxidative phosphorylation and increase mitochondrial respiration without reported plasma membrane depolarization in referenced studies.

Calculate Dose

For research use only.

Key Facts

CAS: 210302-17-3
Molecular Weight (MW): 340.29 g/mol
Half-life: Not established (limited public PK; primarily preclinical/in vitro characterization)
Unit: mg
Administration Route: In vitro / preclinical research use (route varies by study design)
Frequency: Not established
Last updated: 2/23/2026
Targets: Mitochondrial proton gradient (ΔpH/ΔΨm)

Overview

Protocol

Dosage Range: Not established (research-only)
Frequency: Not established
Cycle: Not established (research compound; do not self-administer)
Administration Route: In vitro / preclinical research use (route varies by study design)
Reconstitution Guide: Typically dissolved in DMSO for lab use; follow COA/MSDS and lab SOPs

Science

Mechanism of Action

Acts as a protonophore to uncouple oxidative phosphorylation, increasing respiration while reducing coupling efficiency; reported not to depolarize the plasma membrane.

Targets

Mitochondrial proton gradient (ΔpH/ΔΨm)

Studies

— Journal/year not available
— Journal/year not available

Benefits

Increases mitochondrial respiration via uncoupling (research tool)Used to study energy expenditure and mitochondrial bioenergeticsPreclinical protection reported in mouse ischemia-reperfusion injury models