BAM15
Fat LossMitochondrial uncoupler / small moleculeExperimental
Mitochondrial protonophore uncoupler used in metabolic research to increase energy expenditure independently of beta-oxidation stimulation. Not FDA-approved; not a peptide.
For research use only.
Key Facts
- CAS
- 210302-17-3
- Molecular Weight (MW)
- 340.29 g/mol
- Half-life
- Not established (limited public PK; primarily preclinical/in vitro characterization)
- Unit
- mg
- Administration Route
- In vitro / preclinical research use (route varies by study design)
- Frequency
- Not established
- Last updated
- 8/23/2026
- Targets
- Mitochondrial inner membrane
Overview
Mitochondrial protonophore uncoupler used in metabolic research to increase energy expenditure independently of beta-oxidation stimulation. Not FDA-approved; not a peptide.
Protocol
- Dosage Range
- Not established (research-only)
- Frequency
- Not established
- Cycle
- Not established (research compound; do not self-administer)
- Administration Route
- In vitro / preclinical research use (route varies by study design)
- Reconstitution Guide
- Typically dissolved in DMSO for lab use; follow COA/MSDS and lab SOPs
Science
Mechanism of Action
Increases inner-mitochondrial-membrane proton leak, uncoupling oxidative phosphorylation from ATP synthesis and raising energy expenditure in cells and rodents without the classic DNP-like off-target toxicity profile in published models.
Targets
Mitochondrial inner membrane
Studies
- BAM15 mitochondrial uncouplerโ Journal/year not available
Benefits
Metabolic-rate research toolObesity/diabetes models
Potential Side Effects
- Hyperthermia risk class-effect of uncouplers
- No approved human dose
References
- PMID 23961483External link ยท Year โ
- PubChem BAM15External link ยท Year โ