ARA 290 (Cibinetide)

Fat LossSynthetic Peptide / Tissue Protective (Investigational)

ARA 290, also known as cibinetide, is an 11 amino acid peptide derived from erythropoietin helix B that selectively activates the innate repair receptor to promote anti inflammatory and tissue protective signaling without erythropoietic stimulation.

Calculate Dose

For research use only.

Key Facts

CAS: —
Molecular Weight (MW): ≈1257 g/mol
Half-life: Short plasma half life (reported minutes; tissue protective signaling persists longer in models)
Unit: mg
Administration Route: Subcutaneous (most common in clinical trials)
Frequency: Once daily in many investigational studies
Last updated: 3/3/2026
Targets: Innate Repair Receptor (IRR)EPOR-CD131 heteroreceptor complex

Overview

Protocol

Dosage Range: Dose dependent on clinical protocol; not established for general use
Frequency: Once daily in many investigational studies
Cycle: Investigational protocols vary; not established for consumer use
Administration Route: Subcutaneous (most common in clinical trials)
Reconstitution Guide: Reconstitute per supplier or clinical protocol instructions

Science

Mechanism of Action

Selective agonist of the innate repair receptor complex; activates anti inflammatory and tissue protective signaling without stimulating erythropoiesis.

Targets

Innate Repair Receptor (IRR)EPOR-CD131 heteroreceptor complex

Studies

— Journal/year not available
— Journal/year not available
— Journal/year not available

Benefits

Investigated for small fiber neuropathy symptom reductionStudied for anti inflammatory and tissue protective signalingResearch into metabolic and mitochondrial stress pathways