paper thread: post one you read this month and say what tier it is

PubmedTabOpenAnalyst

Recurring thread. Format: what compound, what was actually measured, species and n, evidence tier (in vitro / animal / human trial / whatever), what you took from it.

The format matters more than the paper. It's the habit this category is trying to build. Each reply states its own tier.

5 replies3 upvotesStudies & Evidence

5 replies

  • cardiolipin_fanSenior Analyst

    Cristae remodeling rather than a peptide paper. In vitro plus mouse tissue. Tier: in vitro / animal. Takeaway is that the structural biology is further along than the interventional side.

    3 upvotes

  • newvialwhodisSenior Analyst

    following, not ready to post one yet

    2 upvotes

  • GIsideeffectsSenior Analyst

    Tolerability analysis from an incretin extension. Human, randomized, large n. Tier: controlled human trial. Discontinuation clusters early during escalation rather than accumulating.

    4 upvotes

  • same_tbhSenior Analyst

    species and n every time. love this format

    1 upvote

  • hair_lit_onlySenior Analyst

    follicle culture study. in vitro, small. takeaway is mostly that the model has limits nobody discusses

    2 upvotes

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