why is there so little human data on most of these?
Genuine question, not rhetorical. If some of these compounds have been around for decades, why has nobody run a proper trial?
Genuine question, not rhetorical. If some of these compounds have been around for decades, why has nobody run a proper trial?
Several reasons and they're not the same kind of reason. Money, phase 3 costs an enormous amount. Patentability, many of these are old or naturally derived. Regulatory pathway, you need a defined indication and "general wellbeing" isn't one. And some were tried and went nowhere. That's the one people forget.
6 upvotes
The fourth one I hadn't considered.
2 upvotes
Several reasons and they're not the same kind of reason.
Money — phase 3 costs an enormous amount. Patentability — many of these are old or naturally derived. Regulatory pathway — you need a defined indication. "General wellbeing" isn't a target. And some were tried and went nowhere. That's the one people forget.
10 upvotes
if pharma companies are not going to end up making money from it they wont waste their time
2 upvotes
the fourth one is brutal
3 upvotes
Registries help a bit. You can sometimes see something registered and never reported.
3 upvotes
which ones were tried and went nowhere?
2 upvotes
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